TOX2 and HSFY2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TOX2	HSFY2
Description		TOX high mobility group box family member 2	heat shock transcription factor Y-linked 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Chromatin DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Colorectal cancer ( 30529582) Conduct disorder (symptom count) ( 20585324) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Red blood cell count ( 27863252 32888494) Refractive error ( 32231278) White blood cell count ( 32888494)
Interacting Genes		24 interacting genes: ANKS1A APP CENPP CSTF2T ENKD1 HCK HOMER3 HSF2BP HSFY1 HSFY2 LGALS4 MFHAS1 NDUFAB1 P4HA3 PHF1 RIBC1 SPG21 TCEA2 TEKT4 TEKT5 TLX3 UNC5CL YPEL3 ZNF461	9 interacting genes: ATXN1 BPIFA1 CCNK DTX2 GCM2 NFYC OTUD7B TBX6 TOX2
Entrez ID		84969	159119
HPRD ID		12734	13680
Ensembl ID		ENSG00000124191	ENSG00000169953
Uniprot IDs		H6UKR8 Q96NM4	Q96LI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Maturation Axonemal A Tubule Inner Sheath	Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Regulation Of RNA Metabolic Process Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Cyclin K-CDK13 Complex Cyclin K-CDK12 Complex Immune Response In Nasopharyngeal-associated Lymphoid Tissue Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism DNA-templated Transcription Negative Regulation Of Neuron Maturation Positive Regulation Of Macromolecule Metabolic Process POZ Domain Binding Immune Response In Gut-associated Lymphoid Tissue Nucleus Regulation Of Gene Expression CCAAT-binding Factor Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Gliogenesis Parathyroid Gland Development Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Poly(G) Binding Mesodermal Cell Fate Specification Cyclin/CDK Positive Transcription Elongation Factor Complex Positive Regulation Of TORC2 Signaling Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Neuron Maturation Intracellular Phosphate Ion Homeostasis Somite Rostral/caudal Axis Specification RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Protein K11-linked Deubiquitination Regulation Of Macromolecule Metabolic Process Nuclear Inclusion Body Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Host-mediated Suppression Of Viral Genome Replication Regulation Of TORC2 Signaling
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