KRT37 and C21orf58

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT37	C21orf58
Description		keratin 37	chromosome 21 open reading frame 58
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Squamous cell lung carcinoma ( 28604730)
Interacting Genes		47 interacting genes: AGXT AQP1 BCAS2 BFSP2 C21orf58 CCDC196 CLCNKA COL8A1 DES FAM110A FBXW5 GNG13 HAPLN2 HGS HOXA1 HSF4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT83 KRT85 KRT86 MTG1 NUFIP2 OIP5 OTX1 PIN1 PKN1 PSMA1 SMARCD1 SMARCE1 TBC1D21 TXLNB USHBP1	14 interacting genes: CCDC125 CCDC136 GRB2 KLHL20 KRT27 KRT35 KRT37 MKRN3 MTUS2 PNMA1 POLR1C SPTA1 TRIB3 USHBP1
Entrez ID		8688	54058
HPRD ID		05175	10755
Ensembl ID		ENSG00000108417	ENSG00000160298
Uniprot IDs		O76014	P58505
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratinization Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Epidermis Development Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Cytosol Developmental Process Cornified Envelope Brahma Complex NpBAF Complex Tissue Development RSC-type Complex NBAF Complex Protein Binding Peptide Cross-linking	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Cytoskeleton Organization Morphogenesis Of An Epithelium Tissue Morphogenesis Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Guanyl-nucleotide Exchange Factor Adaptor Activity Type II Interferon Binding
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