KRT37 and KRT78

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT37	KRT78
Description		keratin 37	keratin 78
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization	Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Squamous cell lung carcinoma ( 28604730)	Aspartate aminotransferase levels ( 33547301) Gamma glutamyl transferase levels ( 29403010)
Interacting Genes		47 interacting genes: AGXT AQP1 BCAS2 BFSP2 C21orf58 CCDC196 CLCNKA COL8A1 DES FAM110A FBXW5 GNG13 HAPLN2 HGS HOXA1 HSF4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT83 KRT85 KRT86 MTG1 NUFIP2 OIP5 OTX1 PIN1 PKN1 PSMA1 SMARCD1 SMARCE1 TBC1D21 TXLNB USHBP1	23 interacting genes: C14orf119 KRT13 KRT14 KRT15 KRT16 KRT19 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 SRPK2 TRIM54 UCHL5
Entrez ID		8688	196374
HPRD ID		05175	17171
Ensembl ID		ENSG00000108417	ENSG00000170423
Uniprot IDs		O76014	Q8N1N4
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratinization Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Epidermis Development Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Cytosol Developmental Process Cornified Envelope Brahma Complex NpBAF Complex Tissue Development RSC-type Complex NBAF Complex Protein Binding Peptide Cross-linking	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Supramolecular Fiber Organization Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Extracellular Exosome Cytosol Developmental Process Hair Cycle Epidermis Development Structural Constituent Of Cytoskeleton Tissue Development Hair Follicle Morphogenesis Intermediate Filament Cytoskeleton Cornified Envelope Protein Binding Keratinocyte Differentiation Keratinization Terminal Web Hair Cycle Process Nuclear Speck Organization
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