LRRFIP1 and FLII

Number of citations of the paper that reports this interaction (PMID 9671805)
11

Data Source:
HPRD (in vitro)

		LRRFIP1	FLII
Gene Name		leucine rich repeat (in FLII) interacting protein 1	flightless I homolog (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane	Nucleoplasm Cytoplasm Microtubule Organizing Center Focal Adhesion
	Molecular Function	DNA Binding Double-stranded RNA Binding Protein Binding Protein Homodimerization Activity	Actin Binding Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Biological_process Positive Regulation Of Type I Interferon Production Innate Immune Response Negative Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Muscle Contraction Multicellular Organismal Development Actin Cytoskeleton Organization Actin Filament Severing
Pathways		Signaling by FGFR in disease Cytosolic sensors of pathogen-associated DNA LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Signaling by FGFR1 mutants Signaling by FGFR mutants Signaling by FGFR1 fusion mutants Innate Immune System
Drugs
Diseases
GWAS		Adiposity ( 22739583)
Protein-Protein Interactions		3 interactors: CEP44 FLII MED4	12 interactors: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MYD88 OPTN PRMT1 TRAIP
Entrez ID		9208	2314
HPRD ID		04460	02647
Ensembl ID		ENSG00000124831	ENSG00000177731
Uniprot IDs		B4DPC0 Q32MZ4	Q13045
PDB IDs		4H22
Enriched GO Terms of Interacting Partners?			Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Modification Signal Transduction Chromatin Organization Peptidyl-arginine N-methylation Signaling Cell Communication Histone Arginine Methylation Intracellular Estrogen Receptor Signaling Pathway Peptidyl-arginine Methylation Response To Stimulus Chromosome Organization Chromatin Remodeling Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling ATP-dependent Chromatin Remodeling Histone H3-R17 Methylation Positive Regulation Of Type I Interferon Production Histone Modification Histone H3-R2 Methylation Cell Development Regulation Of Type I Interferon Production Prostate Epithelial Cord Elongation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Methylation Response To Molecule Of Fungal Origin Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Negative Regulation Of Receptor Recycling Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Interleukin-23 Production Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of RNA Metabolic Process Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Protein Methylation Regulation Of Growth Regulation Of Cellular Process Defense Response Golgi Ribbon Formation Establishment Of Endothelial Intestinal Barrier Regulation Of Organ Morphogenesis Defense Response To Bacterium
Tagcloud ?		abat accuracy biomarkers bisulfite cloning dapp1 diagnosis differential downregulated draft fadd hematologic hypermethylated hypermethylation mds methylation microarray myelodysplastic noninvasive patterns plbd1 profiles refined screened sequencing smpd3 specificity validate validation	a549 accessibility assisted brahma brg1 carm1 chromatin coactivator col1a2 depleted depletion drosophila enhancer faire flightless formaldehyde grip1 homolog isolation notably qpcr recruiting remodeling smad snf swi synergistic tgfbeta transforming
Tagcloud (Difference) ?		abat accuracy biomarkers bisulfite cloning dapp1 diagnosis differential downregulated draft fadd hematologic hypermethylated hypermethylation mds methylation microarray myelodysplastic noninvasive patterns plbd1 profiles refined screened sequencing smpd3 specificity validate validation	a549 accessibility assisted brahma brg1 carm1 chromatin coactivator col1a2 depleted depletion drosophila enhancer faire flightless formaldehyde grip1 homolog isolation notably qpcr recruiting remodeling smad snf swi synergistic tgfbeta transforming
Tagcloud (Intersection) ?