ZMYM3 and ABRAXAS1

Number of citations of the paper that reports this interaction (PubMedID 28242625)
72

Data Source:
BioGRID (pull down)

		ZMYM3	ABRAXAS1
Description		zinc finger MYM-type containing 3	abraxas 1, BRCA1 A complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Nuclear Body BRCA1-A Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Microtubule Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Morphogenesis	DNA Repair Regulation Of DNA Repair Double-strand Break Repair Chromatin Organization DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Attachment Of Spindle Microtubules To Kinetochore Response To Ionizing Radiation Mitotic G2/M Transition Checkpoint Positive Regulation Of DNA Repair Mitotic Spindle Assembly
Pathways			Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: ABRAXAS1 APP CDK6 GTF2I SUMO1 SUMO2 UIMC1	9 interacting genes: AKT1 BABAM1 BRCA1 CFTR OGT SUMO2 UBC UIMC1 ZMYM3
Entrez ID		9203	84142
HPRD ID		02088	08584
Ensembl ID		ENSG00000147130	ENSG00000163322
Uniprot IDs		A8K3Z7 Q14202	Q6UWZ7
PDB IDs			4JLU 4U4A 4Y18 4Y2G
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process BRCA1-A Complex Positive Regulation Of Metabolic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process DNA Damage Response Regulation Of Cell Cycle G2/M Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Protein Tag Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Radiation Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Ubiquitin-like Protein Ligase Binding Presynaptic Cytosol Regulation Of Ubiquitin-dependent Protein Catabolic Process Postsynaptic Cytosol Positive Regulation Of Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Mitotic G2 DNA Damage Checkpoint Signaling Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Presynapse Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Protein Localization To Nucleus Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Protein Sumoylation Negative Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Process Mitotic G2/M Transition Checkpoint Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Glial Cell Development	BRCA1-A Complex Mitotic G2 DNA Damage Checkpoint Signaling Mitotic G2/M Transition Checkpoint Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Mitotic DNA Damage Checkpoint Signaling Ubiquitin-modified Histone Reader Activity Positive Regulation Of DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle DNA Damage Checkpoint Signaling Regulation Of Cell Cycle G2/M Phase Transition Protein Tag Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Response To Radiation Positive Regulation Of DNA Repair Response To Ionizing Radiation Nucleoplasm Signal Transduction In Response To DNA Damage Regulation Of DNA Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition DNA Repair-dependent Chromatin Remodeling Protein K6-linked Ubiquitination Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Cellular Response To Stress Regulation Of Lipid Biosynthetic Process 14-3-3 Protein Binding Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Nucleus Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Phosphatidylinositol-3,4,5-trisphosphate Binding Negative Regulation Of Fatty Acid Metabolic Process Double-strand Break Repair Negative Regulation Of Cell Cycle Phase Transition Regulation Of DNA Repair Protein Modification By Small Protein Conjugation Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Response To Alcohol Negative Regulation Of Cell Cycle Process Regulation Of Cell Cycle Process Protein-containing Complex Ubiquitin Protein Ligase Binding Regulation Of Lipid Metabolic Process Positive Regulation Of TORC1 Signaling
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