FAM175A

Gene Name		family with sequence similarity 175, member A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus BRCA1-A Complex
	Molecular Function	Protein Binding Polyubiquitin Binding
	Biological Process	Double-strand Break Repair Response To Ionizing Radiation Chromatin Modification G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair
Pathways
Drugs
Diseases
GWAS		Upper aerodigestive tract cancers ( 21437268)
Protein-protein Interactions		5 interactors: BRCA1 BRE SUMO2 UBC UIMC1
Entrez ID		84142
HPRD ID		08584
Ensembl ID		ENSG00000163322
Uniprot IDs		D6REL5 Q6UWZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Damage Checkpoint G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Cell Cycle Checkpoint Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Regulation Of Response To DNA Damage Stimulus DNA Repair Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Double-strand Break Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Cellular Metabolic Process Cell Cycle Process DNA Metabolic Process Response To Abiotic Stimulus Cell Cycle Positive Regulation Of Metabolic Process Response To Radiation Cellular Response To Stress Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage Protein Modification By Small Protein Conjugation Regulation Of Cell Cycle Arrest Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Cellular Protein Catabolic Process Protein Polyubiquitination Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Histone H2A K63-linked Deubiquitination Apoptotic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Programmed Cell Death Cell Death Death Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Protein Metabolic Process Cellular Response To Indole-3-methanol Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Centriole Replication
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