LEMD1 and ERMAP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LEMD1	ERMAP
Description		LEM domain containing 1	erythroblast membrane associated protein (Scianna blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process		Regulation Of Cytokine Production T Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Sleep (1/3-day periodicity) ( 33075057)	Red cell distribution width ( 32888494) Visceral fat ( 30942860)
Interacting Genes		13 interacting genes: AQP6 BLCAP EBP ERMAP JAGN1 MEOX2 MGST3 REEP4 RETREG3 SCN3B SLC16A7 TMPPE ZDHHC15	6 interacting genes: CFTR EMD KRTAP3-3 LEMD1 TMEM14A VASP
Entrez ID		93273	114625
HPRD ID		13983	12355
Ensembl ID		ENSG00000186007	ENSG00000164010
Uniprot IDs		Q68G75	A0A1C9HIH9 Q96PL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Organization Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum Pyruvate Secondary Active Transmembrane Transporter Activity Cholesterol-5,6-oxide Hydrolase Activity PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Secondary Active Monocarboxylate Transmembrane Transporter Activity C-8 Sterol Isomerase Activity Cholestenol Delta-isomerase Activity	Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding TMEM240-body Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Cortical Endoplasmic Reticulum Amelogenesis Positive Regulation Of Protein Transport ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Profilin Binding
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