LEMD1 and BLCAP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LEMD1	BLCAP
Description		LEM domain containing 1	BLCAP apoptosis inducing factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleus Cytoplasm Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Apoptotic Process Apoptotic Nuclear Changes
Pathways
Drugs
Diseases
GWAS		Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Sleep (1/3-day periodicity) ( 33075057)	Rheumatoid arthritis ( 30891314)
Interacting Genes		13 interacting genes: AQP6 BLCAP EBP ERMAP JAGN1 MEOX2 MGST3 REEP4 RETREG3 SCN3B SLC16A7 TMPPE ZDHHC15	17 interacting genes: ASGR1 CLDND2 CYSRT1 FAM241B GIMAP1 GJA5 GOSR2 HOXA1 LEMD1 LRAT NOTCH2NLA SKAP1 SLC61A1 SSMEM1 TMEM14B TMEM237 TMEM31
Entrez ID		93273	10904
HPRD ID		13983	16552
Ensembl ID		ENSG00000186007	ENSG00000166619
Uniprot IDs		Q68G75	P62952
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Organization Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum Pyruvate Secondary Active Transmembrane Transporter Activity Cholesterol-5,6-oxide Hydrolase Activity PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Secondary Active Monocarboxylate Transmembrane Transporter Activity C-8 Sterol Isomerase Activity Cholestenol Delta-isomerase Activity	Membrane Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Semicircular Canal Formation O-palmitoyltransferase Activity Phosphatidylcholine-retinol O-acyltransferase Activity Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Asialoglycoprotein Receptor Activity Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Artery Morphogenesis Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication Abducens Nerve Formation Optokinetic Behavior Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Renin Secretion Into Blood Stream Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Regulation Of AV Node Cell Action Potential Cerebral Cortex Development Regulation Of Atrial Cardiac Muscle Cell Action Potential Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication Negative Regulation Of Glomerular Filtration AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling
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