NEK7 and NEK9

Number of citations of the paper that reports this interaction (PMID 20562859)
242

Data Source:
BioGRID (enzymatic study, affinity chromatography technology)
HPRD (in vivo, in vitro)

		NEK7	NEK9
Gene Name		NIMA-related kinase 7	NIMA-related kinase 9
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Microtubule Organizing Center Microtubule	Nucleus Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Cytokinesis Protein Phosphorylation Regulation Of Mitotic Cell Cycle Regulation Of Signal Transduction Spindle Assembly	Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Mitotic Nuclear Envelope Disassembly Cell Division
Pathways		Mitotic Prophase Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Envelope Breakdown Nuclear Pore Complex (NPC) Disassembly Cell Cycle, Mitotic M Phase	Mitotic Prophase Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Envelope Breakdown Nuclear Pore Complex (NPC) Disassembly Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: NEK9	7 interactors: BICD2 MBP NEK6 NEK7 RAN SSRP1 SUPT16H
Entrez ID		140609	91754
HPRD ID		06027	11386
Ensembl ID		ENSG00000151414	ENSG00000119638
Uniprot IDs		B2R8K8 Q8TDX7	Q6PKF2 Q8TD19
PDB IDs		2WQM 2WQN	3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Nucleus Organization	Microtubule Cytoskeleton Organization Spindle Organization Organelle Organization Microtubule-based Process Positive Regulation Of Viral Transcription Transcription Elongation From RNA Polymerase II Promoter Cytoskeleton Organization Regulation Of Viral Transcription Cell Division Positive Regulation Of Viral Process Spindle Assembly DNA-templated Transcription, Elongation Viral Process Cytokinesis Ribosomal Small Subunit Export From Nucleus Defense Response To Nematode Minus-end-directed Organelle Transport Along Microtubule Regulation Of Viral Process Cellular Response To DNA Damage Stimulus Response To Nematode Ribosomal Large Subunit Export From Nucleus Cell Cycle Process Ribosomal Subunit Export From Nucleus DNA Metabolic Process DNA Replication Mitotic Nuclear Division Microtubule Anchoring At Microtubule Organizing Center Cellular Protein Complex Localization Nucleosome Disassembly Negative Regulation Of Interleukin-10 Production Cell Cycle Protein Complex Localization Regulation Of Mitotic Cell Cycle Positive Regulation Of Interleukin-4 Production Positive Regulation Of Macromolecule Biosynthetic Process Response To Mercury Ion Regulation Of Cellular Senescence Cellular Response To Stress Positive Regulation Of Gene Expression Organelle Assembly Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Interleukin-4 Production G2 DNA Damage Checkpoint Mitotic Nuclear Envelope Disassembly Response To Stress Substantia Nigra Development Protein Export From Nucleus Androgen Receptor Signaling Pathway
Tagcloud ?		chip decade delay dimethylation dysplastic elucidated h3k36me2 h3k36me3 hirschhorn hmts ihc immunoblot immunocytochemical knockdown locoregionally malignancy methyltransferase methyltransferases neck nima nsd oncogenic player possesses scchn suboptimal urgently whsc1 wolf	adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network nima p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence
Tagcloud (Difference) ?		chip decade delay dimethylation dysplastic elucidated h3k36me2 h3k36me3 hirschhorn hmts ihc immunoblot immunocytochemical knockdown locoregionally malignancy methyltransferase methyltransferases neck nsd oncogenic player possesses scchn suboptimal urgently whsc1 wolf	adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence
Tagcloud (Intersection) ?		nima