PCSK7 and CSDE1

Number of citations of the paper that reports this interaction (PMID 11051545)
81

Data Source:
HPRD (in vivo)

		PCSK7	CSDE1
Gene Name		proprotein convertase subtilisin/kexin type 7	cold shock domain containing E1, RNA-binding
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Golgi Membrane	Cytoplasm Mitochondrial Inner Membrane Golgi Apparatus Plasma Membrane CRD-mediated MRNA Stability Complex
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity	DNA Binding Poly(A) RNA Binding
	Biological Process	Proteolysis Protein Processing Peptide Hormone Processing	Regulation Of Transcription, DNA-templated Male Gonad Development Nuclear-transcribed MRNA Catabolic Process, No-go Decay
Pathways
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 21943158) Iron status biomarkers ( 21149283)
Protein-Protein Interactions		6 interactors: CSDE1 HNRNPD HSPA5 PABPC1 PMCH SYNCRIP	8 interactors: FAM9B HID1 HNRNPD PABPC1 PCSK7 STT3A SYNCRIP WNK1
Entrez ID		9159	7812
HPRD ID		05339	15949
Ensembl ID			ENSG00000009307
Uniprot IDs		Q16549	G5E9Q2 O75534
PDB IDs			1WFQ 1X65 2YTV 2YTX 2YTY
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Stability Regulation Of RNA Stability MRNA Metabolic Process RNA Catabolic Process MRNA Stabilization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Regulation Of Translation RNA Splicing MRNA Processing Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translation Regulation Of Protein Folding In Endoplasmic Reticulum RNA Processing Catabolic Process Cerebellum Structural Organization Nuclear-transcribed MRNA Catabolic Process Regulation Of Cellular Protein Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, No-go Decay Regulation Of Protein Metabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay CRD-mediated MRNA Stabilization Circadian Regulation Of Translation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process ER Overload Response Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Maintenance Of Protein Localization In Endoplasmic Reticulum Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Regulation Of MRNA 3'-end Processing Cellular Response To Antibiotic Anatomical Structure Arrangement Positive Regulation Of MRNA Catabolic Process Cellular Response To Toxic Substance Cellular Response To Glucose Starvation Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Polyadenylation Cellular Response To Cytokine Stimulus Cerebellar Purkinje Cell Layer Development RNA Polyadenylation Substantia Nigra Development ER-associated Ubiquitin-dependent Protein Catabolic Process Toxin Transport Cellular Response To Interleukin-4 Response To Cytokine	Regulation Of MRNA Stability Regulation Of RNA Stability MRNA Stabilization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Translation RNA Splicing MRNA Processing Positive Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Response To Brefeldin A MRNA Metabolic Process RNA Processing Co-translational Protein Modification Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA Catabolic Process Regulation Of Cellular Protein Metabolic Process CRD-mediated MRNA Stabilization Negative Regulation Of Pancreatic Juice Secretion Circadian Regulation Of Translation Regulation Of Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Positive Regulation Of MRNA Catabolic Process Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Polyadenylation Peptide Hormone Processing RNA Polyadenylation
Tagcloud ?		aric atherogenic atherosclerosis biracial chd close communities confidence dense discovered hazard hazards homogeneous incident insights interval ldl lipid lipoprotein loci locus lowest mellitus newly proportional quartile sdldl traits variants	aiming aip alignment boar brms1 chordc1 clues cops6 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Difference) ?		aric atherogenic atherosclerosis biracial chd close communities confidence dense discovered hazard hazards homogeneous incident insights interval ldl lipid lipoprotein loci locus lowest mellitus newly proportional quartile sdldl traits variants	aiming aip alignment boar brms1 chordc1 clues cops6 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Intersection) ?