CSDE1 and PCSK7

Number of citations of the paper that reports this interaction (PMID 11051545)
81

Data Source:
HPRD (in vivo)

		CSDE1	PCSK7
Gene Name		cold shock domain containing E1, RNA-binding	proprotein convertase subtilisin/kexin type 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Inner Membrane Golgi Apparatus Plasma Membrane CRD-mediated MRNA Stability Complex	Integral Component Of Golgi Membrane
	Molecular Function	DNA Binding Poly(A) RNA Binding	Serine-type Endopeptidase Activity Peptidase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Male Gonad Development Nuclear-transcribed MRNA Catabolic Process, No-go Decay	Proteolysis Protein Processing Peptide Hormone Processing
Pathways
Drugs
Diseases
GWAS			Cardiovascular disease risk factors ( 21943158) Iron status biomarkers ( 21149283)
Protein-Protein Interactions		8 interactors: FAM9B HID1 HNRNPD PABPC1 PCSK7 STT3A SYNCRIP WNK1	6 interactors: CSDE1 HNRNPD HSPA5 PABPC1 PMCH SYNCRIP
Entrez ID		7812	9159
HPRD ID		15949	05339
Ensembl ID		ENSG00000009307
Uniprot IDs		G5E9Q2 O75534	Q16549
PDB IDs		1WFQ 1X65 2YTV 2YTX 2YTY
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Stability Regulation Of RNA Stability MRNA Stabilization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Translation RNA Splicing MRNA Processing Positive Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Response To Brefeldin A MRNA Metabolic Process RNA Processing Co-translational Protein Modification Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA Catabolic Process Regulation Of Cellular Protein Metabolic Process CRD-mediated MRNA Stabilization Negative Regulation Of Pancreatic Juice Secretion Circadian Regulation Of Translation Regulation Of Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Positive Regulation Of MRNA Catabolic Process Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Polyadenylation Peptide Hormone Processing RNA Polyadenylation	Regulation Of MRNA Stability Regulation Of RNA Stability MRNA Metabolic Process RNA Catabolic Process MRNA Stabilization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Regulation Of Translation RNA Splicing MRNA Processing Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translation Regulation Of Protein Folding In Endoplasmic Reticulum RNA Processing Catabolic Process Cerebellum Structural Organization Nuclear-transcribed MRNA Catabolic Process Regulation Of Cellular Protein Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, No-go Decay Regulation Of Protein Metabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay CRD-mediated MRNA Stabilization Circadian Regulation Of Translation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process ER Overload Response Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Maintenance Of Protein Localization In Endoplasmic Reticulum Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Regulation Of MRNA 3'-end Processing Cellular Response To Antibiotic Anatomical Structure Arrangement Positive Regulation Of MRNA Catabolic Process Cellular Response To Toxic Substance Cellular Response To Glucose Starvation Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Polyadenylation Cellular Response To Cytokine Stimulus Cerebellar Purkinje Cell Layer Development RNA Polyadenylation Substantia Nigra Development ER-associated Ubiquitin-dependent Protein Catabolic Process Toxin Transport Cellular Response To Interleukin-4 Response To Cytokine
Tagcloud ?		aiming aip alignment boar brms1 chordc1 clues cops6 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	aric atherogenic atherosclerosis biracial chd close communities confidence dense discovered hazard hazards homogeneous incident insights interval ldl lipid lipoprotein loci locus lowest mellitus newly proportional quartile sdldl traits variants
Tagcloud (Difference) ?		aiming aip alignment boar brms1 chordc1 clues cops6 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	aric atherogenic atherosclerosis biracial chd close communities confidence dense discovered hazard hazards homogeneous incident insights interval ldl lipid lipoprotein loci locus lowest mellitus newly proportional quartile sdldl traits variants
Tagcloud (Intersection) ?