FIBP and FGFBP1

Number of citations of the paper that reports this interaction (PubMedID 11509569)
0

Data Source:
HPRD (in vitro)

		FIBP	FGFBP1
Description		FGF1 intracellular binding protein	fibroblast growth factor binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Endomembrane System Membrane Nuclear Speck	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Membrane
	Molecular Function	Fibroblast Growth Factor Binding	Protein Binding Heparin Binding Fibroblast Growth Factor Binding Growth Factor Binding
	Biological Process	Fibroblast Growth Factor Receptor Signaling Pathway Platelet Aggregation	Signal Transduction Cell-cell Signaling Negative Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Myoblast Proliferation Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Myoblast Proliferation
Pathways			FGFR2b ligand binding and activation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Psoriasis ( 28537254)	Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		10 interacting genes: APP CSNK2A1 CSNK2B DAPK1 FGF1 FGFBP1 GSK3B PKNOX1 RNF32 TENM1	7 interacting genes: ANXA1 ASPH FGF1 FGF2 FIBP HSPG2 UBQLN4
Entrez ID		9158	9982
HPRD ID		08492	06371
Ensembl ID		ENSG00000172500	ENSG00000137440
Uniprot IDs		O43427	Q14512
PDB IDs
Enriched GO Terms of Interacting Partners?		Heparin Binding Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Protein Serine/threonine Kinase Activity Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Migration Regulation Of Cell Population Proliferation PcG Protein Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Autophagy Regulation Of Cell Motility Regulation Of Endothelial Cell Migration Regulation Of Locomotion Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Positive Regulation Of Cell Migration Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Motility Negative Regulation Of Protein Metabolic Process Neuron Projection Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Locomotion Negative Regulation Of Protein Localization To Nucleus Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Transport Cellular Response To Amyloid-beta Signal Transduction Wnt Signaling Pathway Negative Regulation Of Cell Population Proliferation	Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Endothelial Cell Migration Integrin Binding Regulation Of Endothelial Cell Migration Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Epithelial Cell Proliferation Organ Induction Fibroblast Growth Factor Receptor Binding Positive Regulation Of Sprouting Angiogenesis Regulation Of Animal Organ Formation Developmental Induction Positive Regulation Of MAP Kinase Activity Regulation Of Protein Metabolic Process Branching Involved In Ureteric Bud Morphogenesis Regulation Of Cell Population Proliferation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Cell Population Proliferation Regulation Of Anatomical Structure Morphogenesis Regulation Of Vasculature Development Regulation Of Angiogenesis Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Sprouting Angiogenesis Angiogenesis Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of MAP Kinase Activity Regulation Of Morphogenesis Of An Epithelium Regulation Of Epithelial Cell Proliferation Cell Surface Receptor Signaling Pathway Wound Healing Branch Elongation Involved In Ureteric Bud Branching Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Extracellular Matrix Regulation Of Animal Organ Morphogenesis Positive Regulation Of Cell Division Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Endothelial Cell Proliferation Epidermal Cell Differentiation Peptidyl-aspartic Acid 3-dioxygenase Activity Lung Development Response To Wortmannin Positive Regulation Of Inner Ear Receptor Cell Differentiation Positive Regulation Of Cell Fate Specification Positive Regulation Of Lens Fiber Cell Differentiation Positive Regulation Of Inner Ear Auditory Receptor Cell Differentiation Collagen V Binding Nuclear Proteasome Complex Neurogenesis Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Cell Migration
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