ACBD5 and SLC38A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACBD5	SLC38A7
Description		acyl-CoA binding domain containing 5	solute carrier family 38 member 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Membrane	Lysosome Lysosomal Membrane Membrane Axon Cell Projection Neuronal Cell Body
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Lipid Binding	Protein Binding L-asparagine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity
	Biological Process	Pexophagy Fatty Acid Metabolic Process Autophagy Fatty Acid Catabolic Process	Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Asparagine Transport Glutamine Transport
Pathways		Peroxisomal lipid metabolism RHOA GTPase cycle RHOC GTPase cycle Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS			HDL cholesterol levels in HIV infection ( 33109212) Plasma anastrozole concentration in anastrozole-treated estrogen receptor positive breast cancer ( 30648747) QT interval ( 19305408) Schizophrenia ( 25056061 29483656) Suicide attempt severity in mood disorders ( 33783297)
Interacting Genes		4 interacting genes: GRM2 SLC38A7 STX1B TMEM229B	59 interacting genes: ACBD5 AMIGO1 APH1A AQP2 AQP6 AQP9 ARL13B BTNL9 CFTR CLCN7 CLDN7 CLEC10A CPLX4 CREB3L3 CYB561 CYB5R3 EDA ERGIC3 ERP29 EVI2B FAM209A FCER1G FFAR2 FKBP7 GJA8 GJB5 GPR152 GPR42 GPX8 IL10RA KIR2DL3 LMNA LY6G6C LYVE1 MMGT1 MUC1 ODF4 OPRM1 PANX1 PDCD1LG2 RNF5 SAR1A SCN3B SERP2 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC35H1 SPINT1 SSMEM1 SYPL2 TMEM237 TMEM52B TSPAN8 YIPF6
Entrez ID		91452	55238
HPRD ID		12415	07701
Ensembl ID		ENSG00000107897	ENSG00000103042
Uniprot IDs		A0A7I2V2M2 A0A7I2V347 A0A7I2V556 A0A7I2V690 A0A7I2YQE9 B7Z2A7 B7Z2R7 B7Z9D0 Q5T8D3	H3BMC5 Q9NVC3
PDB IDs		3FLV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neurotransmitter Secretion Axon Modulation Of Chemical Synaptic Transmission L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Regulation Of Neurotransmitter Secretion G Protein-coupled Glycine Receptor Activity Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Regulation Of Secretion By Cell Regulation Of Secretion Amino Acid Transport Group II Metabotropic Glutamate Receptor Activity Presynaptic Membrane Positive Regulation Of Synaptic Transmission Asparagine Transport L-asparagine Transmembrane Transporter Activity Regulation Of Synaptic Activity Negative Regulation Of Pinocytosis Intracellular Glutamate Homeostasis Postsynaptic Membrane Regulation Of Spontaneous Synaptic Transmission Spontaneous Neurotransmitter Secretion Regulation Of Response To Drug Carboxylic Acid Transport Organic Acid Transport Glutamine Transport L-glutamine Transmembrane Transporter Activity Behavioral Response To Nicotine Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway Intracellular Amino Acid Homeostasis Calcium Ion-regulated Exocytosis Of Neurotransmitter Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cell Projection Positive Regulation Of Secretion Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming Vesicle Fusion To Plasma Membrane Glutamate Receptor Activity Astrocyte Projection Nuclear Lamina Organic Anion Transport Glutamate Secretion Synaptic Vesicle Membrane Organization G Protein-coupled Receptor Activity Long-term Synaptic Depression G Protein-coupled Glutamate Receptor Signaling Pathway	Membrane Transmembrane Transport Plasma Membrane Protein Binding Organic Hydroxy Compound Transport Water Transport Fluid Transport Channel Activity Water Channel Activity Gap Junction Channel Activity Monoatomic Ion Transport Positive Regulation Of Acute Inflammatory Response Gap Junction Bile Acid:sodium Symporter Activity Endoplasmic Reticulum Basolateral Plasma Membrane Organic Anion Transport Endoplasmic Reticulum Membrane Monoatomic Cation Transport Glycerol Transmembrane Transport Renal Water Transport Monoatomic Anion Channel Activity Polyol Transmembrane Transport Carbohydrate Transmembrane Transport Regulation Of Acute Inflammatory Response Inorganic Ion Transmembrane Transport Carbohydrate Transport Amine Transport Transport Vesicle Membrane Serotonin Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport
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