ACBD5 and TMEM229B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACBD5	TMEM229B
Description		acyl-CoA binding domain containing 5	transmembrane protein 229B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Membrane	Membrane
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Lipid Binding	Protein Binding
	Biological Process	Pexophagy Fatty Acid Metabolic Process Autophagy Fatty Acid Catabolic Process	Response To Bacterium Macrophage Activation
Pathways		Peroxisomal lipid metabolism RHOA GTPase cycle RHOC GTPase cycle Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS			Basophil percentage of white cells ( 32888494) Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Obesity-related traits ( 23251661) Parkinson's disease ( 25064009 28892059) Refractive error ( 32231278) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		4 interacting genes: GRM2 SLC38A7 STX1B TMEM229B	43 interacting genes: ACBD5 AQP6 ARL13B BIK CD53 CD79A CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 GORAB GPX8 HSD17B13 ITGAM LHFPL5 MFF MGST3 MMGT1 MUC1 MYG1 NCR1 NEMP1 PANX1 PIGP PKMYT1 PVR REEP4 SEC22B SLC10A6 SLC39A2 SLC71A2 SYT2 TLCD4 TMEM14B TMEM35A TMEM45B TMPRSS2 TSNARE1 VAPA VSIR
Entrez ID		91452	161145
HPRD ID		12415	08157
Ensembl ID		ENSG00000107897	ENSG00000198133
Uniprot IDs		A0A7I2V2M2 A0A7I2V347 A0A7I2V556 A0A7I2V690 A0A7I2YQE9 B7Z2A7 B7Z2R7 B7Z9D0 Q5T8D3	Q8NBD8
PDB IDs		3FLV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neurotransmitter Secretion Axon Modulation Of Chemical Synaptic Transmission L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Regulation Of Neurotransmitter Secretion G Protein-coupled Glycine Receptor Activity Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Regulation Of Secretion By Cell Regulation Of Secretion Amino Acid Transport Group II Metabotropic Glutamate Receptor Activity Presynaptic Membrane Positive Regulation Of Synaptic Transmission Asparagine Transport L-asparagine Transmembrane Transporter Activity Regulation Of Synaptic Activity Negative Regulation Of Pinocytosis Intracellular Glutamate Homeostasis Postsynaptic Membrane Regulation Of Spontaneous Synaptic Transmission Spontaneous Neurotransmitter Secretion Regulation Of Response To Drug Carboxylic Acid Transport Organic Acid Transport Glutamine Transport L-glutamine Transmembrane Transporter Activity Behavioral Response To Nicotine Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway Intracellular Amino Acid Homeostasis Calcium Ion-regulated Exocytosis Of Neurotransmitter Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cell Projection Positive Regulation Of Secretion Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming Vesicle Fusion To Plasma Membrane Glutamate Receptor Activity Astrocyte Projection Nuclear Lamina Organic Anion Transport Glutamate Secretion Synaptic Vesicle Membrane Organization G Protein-coupled Receptor Activity Long-term Synaptic Depression G Protein-coupled Glutamate Receptor Signaling Pathway	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane
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