MTA1 and DDX18

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		MTA1	DDX18
Gene Name		metastasis associated 1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Microtubule NuRD Complex Intracellular Membrane-bounded Organelle	Nucleolus Membrane
	Molecular Function	Core Promoter Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Double-strand Break Repair Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Response To Ionizing Radiation Response To Lipopolysaccharide Circadian Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Locomotor Rhythm Regulation Of Inflammatory Response Positive Regulation Of Protein Autoubiquitination Negative Regulation Of Nucleic Acid-templated Transcription	Metabolic Process
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: BLOC1S1 CCNH CSNK1G2 DDX18 DYNLL1 ESR1 GPR183 GRB2 HDAC1 HDAC2 HIF1A HIST3H3 IKZF1 ITGB3BP JUN KHDRBS2 KPNA3 KRT40 KRTAP10-8 LMO4 LZTS2 MAGEA11 MBD3 MBD3L2 MNAT1 NACC2 NELFCD NOTCH2NL RBBP4 SAT1 SH3GL1 SH3GLB1 TP53 UBE2I	4 interactors: APP CRMP1 INADL MTA1
Entrez ID		9112	8886
HPRD ID		04633	05894
Ensembl ID		ENSG00000182979	ENSG00000088205
Uniprot IDs		Q13330 Q9BRL8	Q8N254 Q9NVP1
PDB IDs		4BKX	3LY5
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Viral Process ATP-dependent Chromatin Remodeling Regulation Of Viral Transcription RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Cell Proliferation Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Nucleobase-containing Compound Metabolic Process Chromatin Organization Cellular Macromolecule Biosynthetic Process Mitotic Cell Cycle Regulation Of Gene Expression, Epigenetic Macromolecule Biosynthetic Process Positive Regulation Of Receptor Biosynthetic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Receptor Biosynthetic Process Positive Regulation Of Gene Expression Organelle Organization Mitotic Cell Cycle Process Regulation Of Viral Process Multicellular Organismal Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Process Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Complex Assembly Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Protein Autoubiquitination Synaptic Growth At Neuromuscular Junction Regulation Of Protein Autoubiquitination Collateral Sprouting In Absence Of Injury Locomotory Behavior Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Response To Light Stimulus Pyrimidine Nucleobase Catabolic Process Neuron Remodeling Locomotor Rhythm Axon Guidance Response To External Stimulus Response To Radiation Single-organism Behavior Axonogenesis Circadian Behavior Cellular Copper Ion Homeostasis Rhythmic Behavior Axon Development Cell Morphogenesis Involved In Neuron Differentiation Behavior Chemotaxis Entrainment Of Circadian Clock By Photoperiod Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Projection Morphogenesis Photoperiodism Entrainment Of Circadian Clock Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Morphogenesis Involved In Differentiation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Pyrimidine Nucleobase Metabolic Process RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Projection Development Cell Projection Morphogenesis Ionotropic Glutamate Receptor Signaling Pathway Cell Part Morphogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Tight Junction Assembly Axon Cargo Transport
Tagcloud ?		bfls borjeson charged coregulator deacetylase disordered fog1 forssman gal4 homeodomain impair implicates insert lehmann lymphoblastic nucleosome nurd nurf55 overlaps pair phf6 pocket propeller rbbp4 recognizing remodeling repression su top	advance aromatase bioinformatic chipseq coactivator concise contexts coregulatory defines doi endocrine helicase hmgb2 integration october oestrogen onc online partners publication resistant reveals setting src steroid switch switched tamoxifen verified
Tagcloud (Difference) ?		bfls borjeson charged coregulator deacetylase disordered fog1 forssman gal4 homeodomain impair implicates insert lehmann lymphoblastic nucleosome nurd nurf55 overlaps pair phf6 pocket propeller rbbp4 recognizing remodeling repression su top	advance aromatase bioinformatic chipseq coactivator concise contexts coregulatory defines doi endocrine helicase hmgb2 integration october oestrogen onc online partners publication resistant reveals setting src steroid switch switched tamoxifen verified
Tagcloud (Intersection) ?