MTA1

Gene Name		metastasis associated 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Microtubule NuRD Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Core Promoter Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding
	Biological Process	Double-strand Break Repair Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Response To Ionizing Radiation Response To Lipopolysaccharide Circadian Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Locomotor Rhythm Regulation Of Inflammatory Response Positive Regulation Of Protein Autoubiquitination Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-protein Interactions		34 interactors: BLOC1S1 CCNH CSNK1G2 DDX18 DYNLL1 ESR1 GPR183 GRB2 HDAC1 HDAC2 HIF1A HIST3H3 IKZF1 ITGB3BP JUN KHDRBS2 KPNA3 KRT40 KRTAP10-8 LMO4 LZTS2 MAGEA11 MBD3 MBD3L2 MNAT1 NACC2 NELFCD NOTCH2NL RBBP4 SAT1 SH3GL1 SH3GLB1 TP53 UBE2I
Entrez ID		9112
HPRD ID		04633
Ensembl ID		ENSG00000182979
Uniprot IDs		Q13330 Q9BRL8
PDB IDs		4BKX
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Viral Process ATP-dependent Chromatin Remodeling Regulation Of Viral Transcription RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Cell Proliferation Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Nucleobase-containing Compound Metabolic Process Chromatin Organization Cellular Macromolecule Biosynthetic Process Mitotic Cell Cycle Regulation Of Gene Expression, Epigenetic Macromolecule Biosynthetic Process Positive Regulation Of Receptor Biosynthetic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Receptor Biosynthetic Process Positive Regulation Of Gene Expression Organelle Organization Mitotic Cell Cycle Process Regulation Of Viral Process Multicellular Organismal Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Process Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Complex Assembly Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated
Tagcloud ?		bfls borjeson charged coregulator deacetylase disordered fog1 forssman gal4 homeodomain impair implicates insert lehmann lymphoblastic nucleosome nurd nurf55 overlaps pair phf6 pocket propeller rbbp4 recognizing remodeling repression su top