SEC11C and VAMP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEC11C	VAMP4
Description		SEC11 homolog C, signal peptidase complex subunit	vesicle associated membrane protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Signal Peptidase Complex Endoplasmic Reticulum Membrane Membrane	Golgi Membrane Lysosome Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Cell Surface Membrane Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Bounding Membrane Of Organelle Presynaptic Endosome Membrane Glutamatergic Synapse
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity	Protein Binding
	Biological Process	Signal Peptide Processing Proteolysis	Synaptic Vesicle To Endosome Fusion Vesicle-mediated Transport Endocytic Recycling SNARE Complex Assembly Regulation Of Golgi To Plasma Membrane Protein Transport Golgi To Plasma Membrane Protein Transport Cellular Response To Type II Interferon Golgi Ribbon Formation Vesicle-mediated Transport To The Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Regulation Of Synaptic Vesicle Endocytosis
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Maturation of hRSV A proteins	Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Chronotype ( 30696823) Morning person ( 30696823)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal atrophy ( 25625606) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		23 interacting genes: BTN2A2 C2 CADM3 GLP1R HMOX1 MFF PLPP6 PRSS23 RTP2 SCD SELENOM SERP1 STX12 TMEM128 TMEM243 TMEM254 TMEM42 TREX1 TSNARE1 UBE2J1 VAMP1 VAMP4 VAPA	50 interacting genes: ANKS6 AP1M1 AQP6 ARL13B BCL2L13 BIK CD79A CFTR CISD2 CPLX4 CSNK2A1 CYB5R3 DNAJC5 EBP ELOVL4 ERGIC3 EVI2B FAM209A FAM210B GPR152 GPX8 HSD17B13 KASH5 LDLRAD1 LEUTX MFF MGST3 MTIF3 PACS1 PSCA PTGES REEP4 RETREG3 SAR1A SCN3B SEC11C SLC10A6 SLC35H1 SSMEM1 STOM STX16 STX1A STX4 STX6 SYT2 TM4SF19 TMEM205 TMEM51 TMX2 TRIM54
Entrez ID		90701	8674
HPRD ID		15310	06070
Ensembl ID		ENSG00000166562	ENSG00000117533
Uniprot IDs		K7EJQ7 Q9BY50	O75379 Q6IAZ3
PDB IDs		7P2Q
Enriched GO Terms of Interacting Partners?		SNARE Complex Membrane SNAP Receptor Activity Organelle Fusion Vesicle Organization Membrane Fusion SNARE Complex Assembly Establishment Of Protein Localization Organelle Localization By Membrane Tethering Membrane Docking Hormone Secretion Hormone Transport Endoplasmic Reticulum Membrane Vesicle Fusion Organelle Membrane Fusion Endoplasmic Reticulum Synaptic Vesicle Signal Release Glucagon-like Peptide 1 Receptor Activity Monounsaturated Fatty Acid Biosynthetic Process Organic Hydroxy Compound Transport Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process	Membrane SNARE Binding SNARE Complex Vesicle Docking Endoplasmic Reticulum Membrane Organelle Localization By Membrane Tethering Endoplasmic Reticulum SNAP Receptor Activity Membrane Docking Glutathione Peroxidase Activity Synaptic Vesicle Membrane Protein Binding Steroid Biosynthetic Process Synaptic Vesicle Exocytosis Cholesterol Biosynthetic Process Chloride Channel Inhibitor Activity Unsaturated Fatty Acid Metabolic Process ATP-dependent Protein Binding Mitochondrial Membrane Vesicle Fusion Chromaffin Granule Membrane Sterol Biosynthetic Process Organelle Membrane Fusion Small Molecule Biosynthetic Process Vesicle Organization Mitochondrial Outer Membrane Syntaxin Binding Vesicle-mediated Transport SNARE Complex Assembly Organelle Fusion Intracellular Protein Transport Endomembrane System Membrane Fusion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?