CCNF and SCYL1

Number of citations of the paper that reports this interaction (PubMedID 25980818)
0

Data Source:
BioGRID (pull down)

		CCNF	SCYL1
Description		cyclin F	SCY1 like pseudokinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton SCF Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Centrosome Cytosol Cytoskeleton Membrane COPI Vesicle Coat
	Molecular Function	Protein Binding Anaphase-promoting Complex Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	DNA Binding Protein Kinase Activity Protein Binding ATP Binding Cadherin Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Re-entry Into Mitotic Cell Cycle Placenta Development Negative Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Division Regulation Of Cell Cycle	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Inflammatory Response Intracellular Protein Localization Vesicle-mediated Transport Spinal Cord Motor Neuron Differentiation Neuron Development
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs			Grn163l
Diseases
GWAS		Height ( 28552196) Triglyceride levels ( 32203549)	Acne (severe) ( 24927181) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femoral neck bone mineral density ( 22504420) Hip index ( 34021172) Refractive error ( 32231278) Vertical cup-disc ratio ( 20548946)
Interacting Genes		10 interacting genes: AKT1 CCNB1 E2F1 E2F2 E2F3 FZR1 MYBL2 RBPJ SCYL1 SQSTM1	21 interacting genes: APP ARF1 ARF3 AXIN1 CCNF CD93 CDC25A CHD1L COIL COPA COPE DAPK1 DDX6 GORAB LENG1 NOD2 PIN1 PLEKHF2 SMURF1 SNCA TCEA2
Entrez ID		899	57410
HPRD ID		02574	06414
Ensembl ID		ENSG00000162063	ENSG00000142186
Uniprot IDs		P41002 Q59HD0	E9PK59 E9PPN3 Q96KG9
PDB IDs		9CB3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Transcription By RNA Polymerase II Lens Fiber Cell Apoptotic Process Positive Regulation Of Organ Growth Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Positive Regulation Of Metabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Regulator Complex Cis-regulatory Region Sequence-specific DNA Binding Nucleoplasm Regulation Of Organ Growth Anoikis Regulation Of Mitotic Cell Cycle Phase Transition Protein Import Into Nucleus Import Into Nucleus Nucleus Regulation Of Generation Of Precursor Metabolites And Energy RNA Polymerase II Transcription Regulator Complex Macromolecule Biosynthetic Process Labyrinthine Layer Blood Vessel Development Cellular Response To Decreased Oxygen Levels Nucleobase-containing Compound Biosynthetic Process Regulation Of RNA Metabolic Process Anaphase-promoting Complex-dependent Catabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Cell Cycle Phase Transition DNA-binding Transcription Activator Activity Cellular Response To Oxygen Levels Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Kinase Binding Positive Regulation Of Developmental Growth Sequence-specific DNA Binding Regulation Of Cell Population Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Protein Localization To Nucleus Regulation Of Mitotic Cell Cycle Placenta Blood Vessel Development Positive Regulation Of Macromolecule Biosynthetic Process Protein Dimerization Activity Regulation Of Protein Ubiquitination	Positive Regulation Of Catabolic Process Intracellular Transport Regulation Of Protein Metabolic Process Vesicle-mediated Transport Establishment Of Localization In Cell Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Macrophage Activation Protein Localization To Axon Perinuclear Region Of Cytoplasm Intracellular Copper Ion Homeostasis Protein Domain Specific Binding COPI-coated Vesicle Membrane COPI-coated Vesicle COPI Vesicle Coat I-SMAD Binding Positive Regulation Of JNK Cascade Cellular Localization Regulation Of Neurotransmitter Uptake Copper Ion Homeostasis Transport Vesicle Protein Serine/threonine Kinase Binding Cellular Response To Copper Ion Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Cytoplasmic Vesicle R-SMAD Binding Myeloid Leukocyte Activation Amyloid Fibril Formation Establishment Of Protein Localization Growth Cone Microglial Cell Activation Negative Regulation Of Protein Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Response To Copper Ion Regulation Of JNK Cascade Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Leukocyte Activation Involved In Inflammatory Response Golgi Apparatus Mitotic Cleavage Furrow Ingression Intra-Golgi Vesicle-mediated Transport DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Concave Side Of Sperm Head Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cis-trans Isomerase Activity
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