SCYL1 and ARF3

Number of citations of the paper that reports this interaction (PubMedID 30631079)
75

Data Source:
BioGRID (pull down)

		SCYL1	ARF3
Description		SCY1 like pseudokinase 1	ARF GTPase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Centrosome Cytosol Cytoskeleton Membrane COPI Vesicle Coat	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	DNA Binding Protein Kinase Activity Protein Binding ATP Binding Cadherin Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Inflammatory Response Intracellular Protein Localization Vesicle-mediated Transport Spinal Cord Motor Neuron Differentiation Neuron Development	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport
Pathways			Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Grn163l
Diseases
GWAS		Acne (severe) ( 24927181) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femoral neck bone mineral density ( 22504420) Hip index ( 34021172) Refractive error ( 32231278) Vertical cup-disc ratio ( 20548946)	Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)
Interacting Genes		21 interacting genes: APP ARF1 ARF3 AXIN1 CCNF CD93 CDC25A CHD1L COIL COPA COPE DAPK1 DDX6 GORAB LENG1 NOD2 PIN1 PLEKHF2 SMURF1 SNCA TCEA2	18 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 LINC00632 LNX1 PICK1 SCYL1 SLC2A4 SNCA SUMO2
Entrez ID		57410	377
HPRD ID		06414	00056
Ensembl ID		ENSG00000142186	ENSG00000134287
Uniprot IDs		E9PK59 E9PPN3 Q96KG9	P61204
PDB IDs			6II6 8P50
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Catabolic Process Intracellular Transport Regulation Of Protein Metabolic Process Vesicle-mediated Transport Establishment Of Localization In Cell Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Macrophage Activation Protein Localization To Axon Perinuclear Region Of Cytoplasm Intracellular Copper Ion Homeostasis Protein Domain Specific Binding COPI-coated Vesicle Membrane COPI-coated Vesicle COPI Vesicle Coat I-SMAD Binding Positive Regulation Of JNK Cascade Cellular Localization Regulation Of Neurotransmitter Uptake Copper Ion Homeostasis Transport Vesicle Protein Serine/threonine Kinase Binding Cellular Response To Copper Ion Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Cytoplasmic Vesicle R-SMAD Binding Myeloid Leukocyte Activation Amyloid Fibril Formation Establishment Of Protein Localization Growth Cone Microglial Cell Activation Negative Regulation Of Protein Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Response To Copper Ion Regulation Of JNK Cascade Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Leukocyte Activation Involved In Inflammatory Response Golgi Apparatus Mitotic Cleavage Furrow Ingression Intra-Golgi Vesicle-mediated Transport DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Concave Side Of Sperm Head Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cis-trans Isomerase Activity	Protein Domain Specific Binding Protein Transport Intracellular Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Golgi Apparatus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Cell Surface Membrane Curvature Sensor Activity Regulation Of Actin Nucleation Phospholipid Binding Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Catabolic Process Trans-Golgi Network Golgi To Plasma Membrane Transport Perinuclear Region Of Cytoplasm Presynapse Amyloid-beta Binding Establishment Of Localization In Cell Intracellular Transport Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Multicellular Organism Growth Trans-Golgi Network Membrane Small GTPase Binding Golgi Vesicle Transport Phosphatidylinositol Binding Protein Localization To Membrane Chemical Synaptic Transmission Synaptic Vesicle Vesicle-mediated Transport To The Plasma Membrane Trans-synaptic Signaling Monoamine Transport Phosphatidylinositol-4-phosphate Binding Synaptic Signaling Dendritic Spine Regulation Of Supramolecular Fiber Organization Cellular Localization Presynaptic Modulation Of Chemical Synaptic Transmission Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Retrograde Transport, Endosome To Golgi Locomotory Behavior
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?