USP13 and MRPL20

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	MRPL20
Gene Name		ubiquitin specific peptidase 13 (isopeptidase T-3)	mitochondrial ribosomal protein L20
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome	Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Omega Peptidase Activity Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding	Structural Constituent Of Ribosome Protein Binding RRNA Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Autophagy Cell Proliferation Regulation Of Autophagy Melanocyte Differentiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Proteasomal Protein Catabolic Process Protein K63-linked Deubiquitination	Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: DVL1 FNBP1L FUNDC2 LAPTM5 MRPL20 MYO15A PTEN SIAH2 SPRR2C TRIM55 TRIM63 UBC	10 interactors: ACP1 APP CALM2 CAPZB DUSP23 EPS8 ITSN1 OXA1L TP53BP2 USP13
Entrez ID		8975	55052
HPRD ID		04666	14746
Ensembl ID		ENSG00000058056	ENSG00000242485
Uniprot IDs		Q92995	B7Z746 Q9BYC9
PDB IDs		2L80 2LBC
Enriched GO Terms of Interacting Partners?		Prepulse Inhibition Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Catabolic Process Startle Response Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Social Behavior Regulation Of Proteolysis Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cell Projection Morphogenesis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Membrane Organization Cell Part Morphogenesis Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Metabolic Process Positive Regulation Of Ligase Activity Regulation Of Protein Catabolic Process Dendrite Morphogenesis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Canonical Wnt Signaling Pathway Activation Of APC-Cdc20 Complex Activity Postsynaptic Density Assembly Negative Regulation Of Presynaptic Membrane Organization Inner Ear Morphogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Morphogenesis Negative Regulation Of Signal Transduction T Cell Receptor Signaling Pathway Regulation Of Cell Projection Organization Ubiquitin-dependent Protein Catabolic Process Cell Projection Organization Convergent Extension Involved In Neural Plate Elongation Negative Regulation Of Dendritic Spine Morphogenesis Vesicle Transport Along Actin Filament Modification-dependent Protein Catabolic Process	Barbed-end Actin Filament Capping Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Signal Transduction Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Platelet Degranulation Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Polymerization Blood Coagulation Regulation Of Signaling Negative Regulation Of Protein Complex Disassembly Hemostasis Response To Radiation Regulation Of Protein Depolymerization Synaptic Growth At Neuromuscular Junction Mitochondrial Proton-transporting ATP Synthase Complex Assembly Adult Locomotory Behavior Regulation Of Protein Complex Disassembly Negative Regulation Of Protein Complex Assembly Actin Polymerization-dependent Cell Motility Collateral Sprouting In Absence Of Injury Nervous System Development Regulation Of Body Fluid Levels Proton-transporting ATP Synthase Complex Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Wound Healing Negative Regulation Of Cytoskeleton Organization Collateral Sprouting Axon Midline Choice Point Recognition Epidermal Growth Factor Receptor Signaling Pathway Adult Behavior ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Regulation Of Actin Filament Polymerization Movement Of Cell Or Subcellular Component Negative Regulation Of Filopodium Assembly Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity Response To Wounding Exit From Mitosis Axon Choice Point Recognition Platelet Activation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of ATPase Activity
Tagcloud ?		adamts2 aldh1a3 alpl2 apod cabin1 casp10 cdh16 classes classifier clgn covering crabp1 dataset datasets enrichments follicular gnas hmgb2 krthb5 microfollicular nr2f2 nras pax8 predictions sdha separating similarities subclasses timp1	capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese trim45 wars2 zmym6
Tagcloud (Difference) ?		adamts2 aldh1a3 alpl2 apod cabin1 casp10 cdh16 classes classifier clgn covering crabp1 dataset datasets enrichments follicular gnas hmgb2 krthb5 microfollicular nr2f2 nras pax8 predictions sdha separating similarities subclasses timp1	capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese trim45 wars2 zmym6
Tagcloud (Intersection) ?