MGAM and NCF1

Number of citations of the paper that reports this interaction (PMID 16052631)
27

Data Source:
BioGRID (two hybrid)

		MGAM	NCF1
Gene Name		maltase-glucoamylase (alpha-glucosidase)	neutrophil cytosolic factor 1
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Vesicular Exosome	Rough Endoplasmic Reticulum Golgi Apparatus Cytosol Extrinsic Component Of Membrane Dendrite Phagolysosome NADPH Oxidase Complex Neuronal Cell Body
	Molecular Function	Catalytic Activity Glucan 1,4-alpha-glucosidase Activity Alpha-1,4-glucosidase Activity Amylase Activity Carbohydrate Binding Maltose Alpha-glucosidase Activity	Protein Binding Electron Carrier Activity Superoxide-generating NADPH Oxidase Activity SH3 Domain Binding Phosphatidylinositol Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Carbohydrate Metabolic Process Starch Catabolic Process Pathogenesis Polysaccharide Digestion Small Molecule Metabolic Process	Response To Yeast Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Respiratory Burst Involved In Defense Response Protein Targeting To Membrane Leukotriene Metabolic Process Superoxide Metabolic Process Apoptotic Process Inflammatory Response Cellular Defense Response Cell Proliferation Superoxide Anion Generation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Innate Immune Response Respiratory Burst Negative Regulation Of Smooth Muscle Contraction Vascular Endothelial Growth Factor Receptor Signaling Pathway Hydrogen Peroxide Biosynthetic Process Interaction With Host Oxidation-reduction Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Phagosome Maturation
Pathways		Myoclonic epilepsy of Lafora Digestion of dietary carbohydrate Glycogen storage diseases Metabolism of carbohydrates	Signaling by VEGF Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation VEGFA-VEGFR2 Pathway Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System
Drugs		Acarbose Miglitol Voglibose
Diseases
GWAS		Anorexia nervosa ( 23568457)
Protein-Protein Interactions		1 interactors: NCF1	23 interactors: ACTB CSNK2B CYBA FASLG GAA GMNN KHDRBS1 MAPK9 MGAM MSN MYBPC1 MYBPC3 NCF4 NOXA1 PRKCA PRKCB PRKCD PRKCZ PRKDC SRSF2 SYTL1 TRAF4 TRIM9
Entrez ID		8972	653361
HPRD ID		01104
Ensembl ID		ENSG00000257335	ENSG00000158517
Uniprot IDs		E7ER45 O43451	P14598
PDB IDs		2QLY 2QMJ 3CTT 3L4T 3L4U 3L4V 3L4W 3L4X 3L4Y 3L4Z 3TON 3TOP	1GD5 1K4U 1KQ6 1NG2 1O7K 1OV3 1UEC 1W70 1WLP
Enriched GO Terms of Interacting Partners?		Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Respiratory Burst Involved In Defense Response Response To Yeast Killing By Host Of Symbiont Cells Hydrogen Peroxide Biosynthetic Process Respiratory Burst Negative Regulation Of Smooth Muscle Contraction Superoxide Anion Generation Neutrophil Mediated Immunity Negative Regulation Of Muscle Contraction Killing Of Cells Of Other Organism Defense Response To Fungus Leukocyte Mediated Cytotoxicity Interaction With Symbiont Leukotriene Metabolic Process Hydrogen Peroxide Metabolic Process Response To Fungus Superoxide Metabolic Process Phagosome Maturation Regulation Of Smooth Muscle Contraction Cellular Defense Response Defense Response To Gram-positive Bacterium Icosanoid Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Unsaturated Fatty Acid Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Reactive Oxygen Species Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Muscle Contraction Protein Targeting To Membrane Defense Response To Bacterium Antigen Processing And Presentation Of Peptide Antigen Establishment Of Protein Localization To Membrane Leukocyte Mediated Immunity Antigen Processing And Presentation Fatty Acid Metabolic Process Protein Localization To Membrane Protein Targeting Inflammatory Response Response To Bacterium Monocarboxylic Acid Metabolic Process	Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Histone H3-T6 Phosphorylation Platelet Activation Positive Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process Peptidyl-threonine Phosphorylation Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Immune Response Apoptotic Signaling Pathway Apoptotic Process Regulation Of Catalytic Activity Programmed Cell Death Cell Activation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Phospholipase Activity Cell Death Regulation Of Protein Phosphorylation Death Blood Coagulation Regulation Of Cellular Protein Metabolic Process Hemostasis Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity Cellular Response To Carbohydrate Stimulus Organelle Organization Mitotic Cell Cycle Positive Regulation Of Lipase Activity Response To Interleukin-1 Innate Immune Response Regulation Of Glucose Transport Regulation Of Platelet Aggregation Regulation Of Protein Metabolic Process Muscle System Process Negative Regulation Of Glucose Transport Signaling Regulation Of Phosphorylation Regulation Of Immune System Process Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Protein Phosphorylation Peptidyl-serine Phosphorylation
Tagcloud ?		annotation cbs degs description devastating diffuse downloaded etiology foundation fpr1 gse idiopathic iips il1r2 interstitial kinds mt1x parenchymal played pneumonias ppi profiling s100a12 screened sdr16c5 serpina3 slco4a1 subtypes underscores	anticancer atlas ccle computational consequences cosmic driver encyclopedia harboring identifying illustrated investigating mapped midostaurin nucleic onto plek pocket precision projects researchers rwdd1 somatic tcga tended tipifarnib uncover vav3 vinorelbine
Tagcloud (Difference) ?		annotation cbs degs description devastating diffuse downloaded etiology foundation fpr1 gse idiopathic iips il1r2 interstitial kinds mt1x parenchymal played pneumonias ppi profiling s100a12 screened sdr16c5 serpina3 slco4a1 subtypes underscores	anticancer atlas ccle computational consequences cosmic driver encyclopedia harboring identifying illustrated investigating mapped midostaurin nucleic onto plek pocket precision projects researchers rwdd1 somatic tcga tended tipifarnib uncover vav3 vinorelbine
Tagcloud (Intersection) ?