MGAM

Description		maltase-glucoamylase
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Catalytic Activity Glucan 1,4-alpha-glucosidase Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Alpha-1,4-glucosidase Activity Oligo-1,6-glucosidase Activity Protein Binding Amylase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Carbohydrate Binding Alpha-glucosidase Activity
	Biological Process	Maltose Catabolic Process Carbohydrate Metabolic Process Starch Catabolic Process Disaccharide Catabolic Process Dextrin Catabolic Process
Pathways		Digestion of dietary carbohydrate Neutrophil degranulation
Drugs		Acarbose Miglitol Voglibose
Diseases
GWAS		1,5-anhydroglucitol levels ( 28588231) Anorexia nervosa ( 23568457) Idiopathic dilated cardiomyopathy ( 29495422)
Novel Interacting Genes		1 novel interacting genes: ARF6
Interacting Genes		7 interacting genes: AQP6 CPLX4 CREB3L1 GPR42 NCF1 SLC18A1 TMEM14B
Entrez ID		8972
HPRD ID		01104
Ensembl ID		ENSG00000257335
Uniprot IDs		O43451
PDB IDs		2QLY 2QMJ 3CTT 3L4T 3L4U 3L4V 3L4W 3L4X 3L4Y 3L4Z 3TON 3TOP
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Membrane Vesicle-mediated Transport In Synapse Erythrocyte Apoptotic Process Neurotransmitter Transport Terminal Bouton Aminergic Neurotransmitter Loading Into Synaptic Vesicle Neutrophil-mediated Killing Of Fungus Monoatomic Anion Channel Activity Carbon Dioxide Transmembrane Transporter Activity Ammonium Transmembrane Transport Ammonium Channel Activity Renal Water Transport Carbon Dioxide Transmembrane Transport Thioesterase Binding Positive Regulation Of Keratinocyte Migration Presynapse Maintenance Of Postsynaptic Specialization Structure Positive Regulation Of Mitotic Cytokinetic Process Cellular Response To Diacyl Bacterial Lipopeptide Negative Regulation Of Dendrite Development Protein Localization To Cleavage Furrow Positive Regulation Of Focal Adhesion Disassembly Cellular Response To Bacterial Lipopeptide Maintenance Of Postsynaptic Density Structure Monoamine:proton Antiporter Activity Serotonin Uptake Amine Transport Clathrin-sculpted Monoamine Transport Vesicle Membrane Serotonin:sodium:chloride Symporter Activity Catecholamine Uptake Dopamine Uptake Norepinephrine Transport Monoamine Transmembrane Transporter Activity Norepinephrine Uptake Neurotransmitter Loading Into Synaptic Vesicle Extracellular Matrix Constituent Secretion Neutrophil-mediated Killing Of Gram-positive Bacterium Neutrophil-mediated Killing Of Bacterium Respiratory Burst Involved In Defense Response Phagolysosome Hydrogen Peroxide Biosynthetic Process Cellular Response To Testosterone Stimulus Superoxide-generating NAD(P)H Oxidase Activity Regulation Of Respiratory Burst Involved In Inflammatory Response Superoxide-generating NADPH Oxidase Activator Activity
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