TIMELESS and TIPIN

Number of citations of the paper that reports this interaction (PMID 12875843)
28

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TIMELESS	TIPIN
Gene Name		timeless circadian clock	TIMELESS interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleolus Microtubule Cytoskeleton	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Morphogenesis Of An Epithelium Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Mitotic Nuclear Division Circadian Rhythm Detection Of Abiotic Stimulus Response To Abiotic Stimulus Lung Development Regulation Of Cell Proliferation Regulation Of Circadian Rhythm Cell Cycle Phase Transition Negative Regulation Of Transcription, DNA-templated Branching Morphogenesis Of An Epithelial Tube Cell Division	DNA Replication Checkpoint Mitotic Nuclear Division Positive Regulation Of Cell Proliferation Response To UV Intra-S DNA Damage Checkpoint Regulation Of Nuclear Cell Cycle DNA Replication Cell Cycle Phase Transition Replication Fork Protection Cell Division
Pathways
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		9 interactors: CHEK1 CRY1 CRY2 PCBD1 PER1 PER2 TF TIPIN ZSCAN1	3 interactors: APP TEX11 TIMELESS
Entrez ID		8914	54962
HPRD ID		04864	16917
Ensembl ID		ENSG00000111602
Uniprot IDs		Q9UNS1	G8JLE5 Q9BVW5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Response To Light Stimulus Photoperiodism Entrainment Of Circadian Clock Blue Light Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Response To Radiation Circadian Rhythm Response To Blue Light Circadian Regulation Of Translation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process DNA Damage Induced Protein Phosphorylation Rhythmic Process Cellular Response To Light Stimulus Protein-chromophore Linkage Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Cellular Response To Radiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Abiotic Stimulus Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Histone H3 Deacetylation RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gluconeogenesis Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Histone Deacetylation Hexose Biosynthetic Process Protein Deacetylation Histone Modification RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription, Termination	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Meiotic Gene Conversion Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Meiosis Chromosome Segregation Axon Choice Point Recognition Chiasma Assembly Neuron Remodeling Resolution Of Meiotic Recombination Intermediates Organ Development Cellular Copper Ion Homeostasis Chromosome Separation Copper Ion Homeostasis Suckling Behavior Synaptonemal Complex Assembly Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Synaptonemal Complex Organization Sexual Reproduction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway System Development Reproduction Cell Cycle Process Ionotropic Glutamate Receptor Signaling Pathway Reciprocal Meiotic Recombination Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Response To Abiotic Stimulus Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Synapsis Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Homologous Chromosome Segregation Nucleobase-containing Compound Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Male Meiosis Visual Learning Glutamate Receptor Signaling Pathway Multicellular Organismal Development
Tagcloud ?		ancestral anthropogenic arthropod calanus californicus circadian clock clockwork copepod copepods crustacean cryptochrome daphnia doubletime finmarchicus inputs intertidal orange pacemaker publicly pulex rhythms shaggy stressor stressors suite supernumerary tigriopus vrille	architecture associates auroras catenated cdk1 centromere centromeres centromeric chromatid claspin cohesion colocalized coordinate coordinates exit fork mitosis mitotic plk1 polo repeats s10 satellite sister spindle telomeres termination tim timeless
Tagcloud (Difference) ?		ancestral anthropogenic arthropod calanus californicus circadian clock clockwork copepod copepods crustacean cryptochrome daphnia doubletime finmarchicus inputs intertidal orange pacemaker publicly pulex rhythms shaggy stressor stressors suite supernumerary tigriopus vrille	architecture associates auroras catenated cdk1 centromere centromeres centromeric chromatid claspin cohesion colocalized coordinate coordinates exit fork mitosis mitotic plk1 polo repeats s10 satellite sister spindle telomeres termination tim
Tagcloud (Intersection) ?		timeless