TIPIN and TIMELESS

Number of citations of the paper that reports this interaction (PMID 12875843)
28

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TIPIN	TIMELESS
Gene Name		TIMELESS interacting protein	timeless circadian clock
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle	Nuclear Chromatin Nucleus Nucleolus Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	DNA Replication Checkpoint Mitotic Nuclear Division Positive Regulation Of Cell Proliferation Response To UV Intra-S DNA Damage Checkpoint Regulation Of Nuclear Cell Cycle DNA Replication Cell Cycle Phase Transition Replication Fork Protection Cell Division	Negative Regulation Of Transcription From RNA Polymerase II Promoter Morphogenesis Of An Epithelium Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Mitotic Nuclear Division Circadian Rhythm Detection Of Abiotic Stimulus Response To Abiotic Stimulus Lung Development Regulation Of Cell Proliferation Regulation Of Circadian Rhythm Cell Cycle Phase Transition Negative Regulation Of Transcription, DNA-templated Branching Morphogenesis Of An Epithelial Tube Cell Division
Pathways
Drugs
Diseases
GWAS			Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		3 interactors: APP TEX11 TIMELESS	9 interactors: CHEK1 CRY1 CRY2 PCBD1 PER1 PER2 TF TIPIN ZSCAN1
Entrez ID		54962	8914
HPRD ID		16917	04864
Ensembl ID			ENSG00000111602
Uniprot IDs		G8JLE5 Q9BVW5	Q9UNS1
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Meiotic Gene Conversion Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Meiosis Chromosome Segregation Axon Choice Point Recognition Chiasma Assembly Neuron Remodeling Resolution Of Meiotic Recombination Intermediates Organ Development Cellular Copper Ion Homeostasis Chromosome Separation Copper Ion Homeostasis Suckling Behavior Synaptonemal Complex Assembly Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Synaptonemal Complex Organization Sexual Reproduction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway System Development Reproduction Cell Cycle Process Ionotropic Glutamate Receptor Signaling Pathway Reciprocal Meiotic Recombination Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Response To Abiotic Stimulus Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Synapsis Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Homologous Chromosome Segregation Nucleobase-containing Compound Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Male Meiosis Visual Learning Glutamate Receptor Signaling Pathway Multicellular Organismal Development	Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Response To Light Stimulus Photoperiodism Entrainment Of Circadian Clock Blue Light Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Response To Radiation Circadian Rhythm Response To Blue Light Circadian Regulation Of Translation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process DNA Damage Induced Protein Phosphorylation Rhythmic Process Cellular Response To Light Stimulus Protein-chromophore Linkage Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Cellular Response To Radiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Abiotic Stimulus Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Histone H3 Deacetylation RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gluconeogenesis Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Histone Deacetylation Hexose Biosynthetic Process Protein Deacetylation Histone Modification RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription, Termination
Tagcloud ?		architecture associates auroras catenated cdk1 centromere centromeres centromeric chromatid claspin cohesion colocalized coordinate coordinates exit fork mitosis mitotic plk1 polo repeats s10 satellite sister spindle telomeres termination tim timeless	ancestral anthropogenic arthropod calanus californicus circadian clock clockwork copepod copepods crustacean cryptochrome daphnia doubletime finmarchicus inputs intertidal orange pacemaker publicly pulex rhythms shaggy stressor stressors suite supernumerary tigriopus vrille
Tagcloud (Difference) ?		architecture associates auroras catenated cdk1 centromere centromeres centromeric chromatid claspin cohesion colocalized coordinate coordinates exit fork mitosis mitotic plk1 polo repeats s10 satellite sister spindle telomeres termination tim	ancestral anthropogenic arthropod calanus californicus circadian clock clockwork copepod copepods crustacean cryptochrome daphnia doubletime finmarchicus inputs intertidal orange pacemaker publicly pulex rhythms shaggy stressor stressors suite supernumerary tigriopus vrille
Tagcloud (Intersection) ?		timeless