GYG2 and GYS2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GYG2	GYS2
Gene Name		glycogenin 2	glycogen synthase 2 (liver)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cytoplasm Cytosol Cytoskeleton Cell Cortex Cortical Actin Cytoskeleton Ectoplasm
	Molecular Function	Glycogenin Glucosyltransferase Activity	Glycogen (starch) Synthase Activity Protein Homodimerization Activity Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Pathogenesis Small Molecule Metabolic Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Generation Of Precursor Metabolites And Energy Pathogenesis Response To Glucose Small Molecule Metabolic Process
Pathways		Glucose metabolism Glycogen breakdown (glycogenolysis) Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates	Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP GYG1 GYS1 GYS2 IKBKG	2 interactors: GYG2 TNFRSF1A
Entrez ID		8908	2998
HPRD ID		02185	00722
Ensembl ID		ENSG00000056998	ENSG00000111713
Uniprot IDs		B3KUV6 O15488 Q1ZYL7	P54840
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycogen Biosynthetic Process Cellular Polysaccharide Biosynthetic Process Polysaccharide Biosynthetic Process Glycogen Metabolic Process Polysaccharide Metabolic Process Energy Reserve Metabolic Process Glucose Metabolic Process Carbohydrate Biosynthetic Process Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Monosaccharide Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Generation Of Precursor Metabolites And Energy Synaptic Growth At Neuromuscular Junction Small Molecule Metabolic Process Collateral Sprouting In Absence Of Injury Intracellular Receptor Signaling Pathway Carbohydrate Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Oxidation-reduction Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Glycogen Catabolic Process Cellular Copper Ion Homeostasis Polysaccharide Catabolic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cellular Carbohydrate Catabolic Process Positive Regulation Of NIK/NF-kappaB Signaling Mating Behavior Biosynthetic Process B Cell Homeostasis Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling	Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Positive Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Glycogen Catabolic Process Regulation Of Protein Import Into Nucleus, Translocation Cellular Response To Estradiol Stimulus Polysaccharide Catabolic Process Glycogen Biosynthetic Process Cellular Response To Estrogen Stimulus Prostaglandin Metabolic Process Cellular Carbohydrate Catabolic Process Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Interleukin-6 Production Cellular Polysaccharide Biosynthetic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Polysaccharide Biosynthetic Process Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Tumor Necrosis Factor Production Glycogen Metabolic Process Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of JAK-STAT Cascade Cellular Response To Mechanical Stimulus Positive Regulation Of Neuron Death Tetrapyrrole Metabolic Process Polysaccharide Metabolic Process Regulation Of JAK-STAT Cascade Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Inflammatory Response Regulation Of Tumor Necrosis Factor Production Icosanoid Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cellular Response To Tumor Necrosis Factor Regulation Of Interleukin-6 Production Unsaturated Fatty Acid Metabolic Process Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Inflammatory Response Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Response To Amino Acid Small Molecule Metabolic Process Response To Estradiol Response To Tumor Necrosis Factor Positive Regulation Of Angiogenesis Protein Heterooligomerization Energy Reserve Metabolic Process Response To Ethanol Glucose Metabolic Process Response To Alkaloid Carbohydrate Biosynthetic Process Carbohydrate Catabolic Process
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