IL18RAP and CD48

Number of citations of the paper that reports this interaction (PMID 15760905)
5

Data Source:
HPRD (in vivo)

		IL18RAP	CD48
Gene Name		interleukin 18 receptor accessory protein	CD48 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Anchored Component Of Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity	Receptor Activity Protein Binding
	Biological Process	Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway	Defense Response Blood Coagulation Leukocyte Migration
Pathways			Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Celiac disease ( 20190752 18311140) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		3 interactors: APP CD48 IL18	10 interactors: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK
Entrez ID		8807	962
HPRD ID		05147	00177
Ensembl ID		ENSG00000115607	ENSG00000117091
Uniprot IDs		O95256 Q3KPE8	P09326
PDB IDs			2EDO
Enriched GO Terms of Interacting Partners?		Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process Chemokine Biosynthetic Process Interleukin-13 Biosynthetic Process Defense Response Synaptic Growth At Neuromuscular Junction Interferon-gamma Biosynthetic Process Collateral Sprouting In Absence Of Injury Positive Regulation Of NK T Cell Proliferation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Interleukin-2 Biosynthetic Process Immune System Process Axon Choice Point Recognition Positive Regulation Of Natural Killer Cell Proliferation Regulation Of Natural Killer Cell Proliferation Chemokine Metabolic Process Blood Coagulation Hemostasis Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Neuron Remodeling Interleukin-2 Production Chemokine Production Type 2 Immune Response Positive Regulation Of Interleukin-17 Production Regulation Of Body Fluid Levels Positive Regulation Of Alpha-beta T Cell Proliferation Wound Healing Sleep Cellular Copper Ion Homeostasis Cell Activation Interferon-gamma Production Response To Wounding Positive Regulation Of NF-kappaB Import Into Nucleus Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Cell Differentiation Negative Regulation Of Myoblast Differentiation Positive Regulation Of Activated T Cell Proliferation Cytokine Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Stress Positive Regulation Of Natural Killer Cell Activation T-helper 1 Type Immune Response Positive Regulation Of Tissue Remodeling Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cytokine Metabolic Process Mating Behavior	Regulation Of Defense Response To Virus By Virus Blood Coagulation Hemostasis Leukocyte Migration Regulation Of Body Fluid Levels Wound Healing T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation T Cell Costimulation Cell Activation Regulation Of T Cell Activation Regulation Of Defense Response To Virus Positive Regulation Of Cell Activation Immune System Process Response To Wounding Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Signal Transduction T Cell Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Lymphocyte Activation Signaling Antigen Receptor-mediated Signaling Pathway Cell Communication Regulation Of Cell Activation Leukocyte Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Single Organismal Cell-cell Adhesion Cell Surface Receptor Signaling Pathway Platelet Activation Cellular Response To Stimulus Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immune Response Response To Stress Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Interferon-gamma Production Positive Regulation Of Intracellular Signal Transduction Cell Migration Natural Killer Cell Activation Cell Motility Positive Regulation Of Immune System Process
Tagcloud ?		ahsa2 cd coeliac ddx59 egenes elmo1 eprobes eqtl eqtls esnps harbour implies nominal nsf overlapped park7 pbmc rs12727642 rs13003464 rs2074404 rs2298428 rs296547 rs6974491 rs842647 rs917997 snps thymic thymus ube2l3	advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Difference) ?		ahsa2 cd coeliac ddx59 egenes elmo1 eprobes eqtl eqtls esnps harbour implies nominal nsf overlapped park7 pbmc rs12727642 rs13003464 rs2074404 rs2298428 rs296547 rs6974491 rs842647 rs917997 snps thymic thymus ube2l3	advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Intersection) ?