TNFRSF10D and TNFSF10

Number of citations of the paper that reports this interaction (PMID 9430226)
103

Data Source:
HPRD (in vivo, in vitro)

		TNFRSF10D	TNFSF10
Gene Name		tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain	tumor necrosis factor (ligand) superfamily, member 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Extracellular Space Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity TRAIL Binding	Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Signal Transduction Negative Regulation Of Apoptotic Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Cell-cell Signaling Male Gonad Development Response To Insulin Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Regulation by c-FLIP Death Receptor Signalling TRAIL signaling Dimerization of procaspase-8 Caspase-8 activation by cleavage Programmed Cell Death Extrinsic Pathway
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732625)
Protein-Protein Interactions		3 interactors: TNFRSF10A TNFRSF10B TNFSF10	9 interactors: ACP5 CASP3 RBM48 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11B ZDHHC17
Entrez ID		8793	8743
HPRD ID		04682	04670
Ensembl ID		ENSG00000173530	ENSG00000121858
Uniprot IDs		Q9UBN6	P50591 Q6IBA9
PDB IDs			1D0G 1D2Q 1D4V 1DG6 1DU3
Enriched GO Terms of Interacting Partners?		Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Protein Processing Positive Regulation Of Proteolysis Apoptotic Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Positive Regulation Of NIK/NF-kappaB Signaling NIK/NF-kappaB Signaling Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Proteolysis Cellular Response To Mechanical Stimulus Positive Regulation Of Intracellular Signal Transduction Extrinsic Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Positive Regulation Of Hydrolase Activity Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Apoptotic Process Response To Mechanical Stimulus Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Catalytic Activity Regulation Of Cell Death TRAIL-activated Apoptotic Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Protein Kinase Activity	Apoptotic Process Programmed Cell Death Cell Death Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Activation Of NF-kappaB-inducing Kinase Activity Protein Processing Positive Regulation Of NIK/NF-kappaB Signaling NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Proteolysis Apoptotic Signaling Pathway Signal Transduction Response To Stimulus Regulation Of Endopeptidase Activity Cellular Response To Mechanical Stimulus Regulation Of Peptidase Activity Signaling Cell Communication Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Superoxide Anion Generation Positive Regulation Of Apoptotic Process Cellular Response To Stimulus Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death TRAIL-activated Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Proteolysis Regulation Of Protein Kinase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intrinsic Apoptotic Signaling Pathway Regulation Of Kinase Activity Response To External Stimulus Negative Regulation Of Odontogenesis Riboflavin Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Glial Cell Apoptotic Process
Tagcloud ?			adenovirus apobec3a ddx58 exact expand hiv ifi27 ifi44l ifit1 ifit2 ifit3 innate irf7 isg15 isg20 isgs mdms microarray monocyte mx1 mx2 reservoirs rig rsad2 select stat1 trail viperin vpr
Tagcloud (Difference) ?			adenovirus apobec3a ddx58 exact expand hiv ifi27 ifi44l ifit1 ifit2 ifit3 innate irf7 isg15 isg20 isgs mdms microarray monocyte mx1 mx2 reservoirs rig rsad2 select stat1 trail viperin vpr
Tagcloud (Intersection) ?