TNFRSF10D and SEMA4G

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TNFRSF10D	SEMA4G
Name		TNF receptor superfamily member 10d	semaphorin 4G
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane	Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Apoptotic Process Signal Transduction Negative Regulation Of Apoptotic Process	Neural Crest Cell Migration Nervous System Development Axon Guidance Cell Differentiation Positive Regulation Of Cell Migration Negative Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways		Cell surface interactions at the vascular wall TP53 Regulates Transcription of Death Receptors and Ligands TRAIL signaling	None
GWAS		Attention deficit hyperactivity disorder ( 20732625 ) Lymphocyte percentage of white cells ( 32888494 )	Regular attendance at a pub or social club ( 29970889 )
Interacting Genes		28 interacting genes: APOL3 ARFIP1 CIAO2A ECPAS FAM114A1 GAD2 HSBP1L1 INPP5K LAT MIEF1 MTERF4 PCYT1A PITPNC1 PLPP6 POLL RBP1 RMDN2 SEMA4G SENP2 SLC39A7 SUCLA2 TARS2 TBRG4 THAP4 TNFRSF10A TNFRSF10B TNFSF10 TUFM	12 interacting genes: ARL13B ATXN1 CAMK2B CREB3L1 DEGS1 DLG4 GOPC LIG4 RBPMS TNFRSF10D TRIP13 ZDHHC17
Entrez ID		8793	57715
HPRD ID		04682	10218
Ensembl ID		ENSG00000173530	ENSG00000095539
Uniprot IDs		Q9UBN6	Q9NTN9 Q9NWU8
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		TRAIL Binding TRAIL-activated Apoptotic Signaling Pathway Death Receptor Activity Lipid Phosphatase Activity Succinate Metabolic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Mitochondrial RNA Metabolic Process Activation Of NF-kappaB-inducing Kinase Activity	Golgi-associated Vesicle Membrane Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Neurogenesis Postsynaptic Density Positive Regulation Of Nervous System Development Identical Protein Binding Regulation Of Long-term Neuronal Synaptic Plasticity P2Y1 Nucleotide Receptor Binding Social Behavior Establishment Of Integrated Proviral Latency Sphingolipid Delta-4 Desaturase Activity Perforant Pathway To Dendrate Granule Cell Synapse Negative Regulation Of Anion Channel Activity