GNAT1 and RGS9

Number of citations of the paper that reports this interaction (PMID 12119397)
60

Data Source:
HPRD (in vivo)

		GNAT1	RGS9
Gene Name		guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	regulator of G-protein signaling 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytosol Heterotrimeric G-protein Complex Plasma Membrane Membrane Apical Plasma Membrane Photoreceptor Connecting Cilium Photoreceptor Outer Segment Membrane Neuronal Cell Body Photoreceptor Disc Membrane	Nucleus Cytoplasm Heterotrimeric G-protein Complex Plasma Membrane
	Molecular Function	Acyl Binding G-protein Coupled Receptor Binding GTPase Activity Signal Transducer Activity GTP Binding GDP Binding Protein Kinase Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding	Signal Transducer Activity GTPase Activator Activity Protein Complex Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Visual Perception Phototransduction, Visible Light Cell Proliferation Response To Light Stimulus Response To Light Intensity Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Eye Photoreceptor Cell Development Detection Of Light Stimulus Involved In Visual Perception Sensory Perception Of Umami Taste Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus	Dopamine Receptor Signaling Pathway Nervous System Development Visual Perception Phototransduction, Visible Light Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity Response To Estrogen
Pathways		Signaling by GPCR PLC beta mediated events Opioid Signalling G-protein mediated events Diseases associated with visual transduction Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade GPCR downstream signaling Visual phototransduction G-protein activation The phototransduction cascade G alpha (i) signalling events	Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: F2R RGS16 RGS9	5 interactors: ADRB2 GNAT1 GNB5 GUCY2D RGS9BP
Entrez ID		2779	8787
HPRD ID		08850	04962
Ensembl ID			ENSG00000108370
Uniprot IDs		P11488	A8K1G1 O75916
PDB IDs		3RBQ
Enriched GO Terms of Interacting Partners?		Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Hydrolase Activity Negative Regulation Of Renin Secretion Into Blood Stream Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Sensory Perception Of Light Stimulus Positive Regulation Of Catalytic Activity Establishment Of Synaptic Specificity At Neuromuscular Junction Connective Tissue Replacement Involved In Inflammatory Response Wound Healing STAT Protein Import Into Nucleus Negative Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Interleukin-6 Secretion Wound Healing Involved In Inflammatory Response Regulation Of Catalytic Activity Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Interleukin-8 Secretion Platelet Dense Granule Organization Thrombin Receptor Signaling Pathway Regulation Of Glomerular Filtration Regulation Of Signal Transduction Regulation Of Interleukin-8 Secretion Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Regulation Of Signaling Positive Regulation Of GTPase Activity Positive Regulation Of Metabolic Process Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Collagen Biosynthetic Process Regulation Of Sensory Perception Of Pain Sensory Perception Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Collagen Metabolic Process Response To Lipid Rhodopsin Mediated Signaling Pathway Positive Regulation Of Interleukin-8 Production Positive Regulation Of Vasoconstriction Positive Regulation Of Blood Coagulation Dopamine Receptor Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Rho Protein Signal Transduction Regulation Of Collagen Metabolic Process Positive Regulation Of Calcium Ion Transport Into Cytosol Homeostasis Of Number Of Cells Within A Tissue Regulation Of Sequestering Of Calcium Ion Secretory Granule Organization Positive Regulation Of Coagulation	Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Detection Of Light Stimulus Cellular Response To Radiation Detection Of Abiotic Stimulus Response To Light Stimulus Response To Abiotic Stimulus G-protein Coupled Receptor Signaling Pathway Response To Radiation Detection Of Stimulus Response To External Stimulus Detection Of Light Stimulus Involved In Visual Perception Visual Perception Sensory Perception Of Light Stimulus Regulation Of Signal Transduction Regulation Of Signaling Cell Surface Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Sensory Perception G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Signal Transduction Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Signaling Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Cell Communication Neurological System Process Negative Regulation Of Voltage-gated Calcium Channel Activity Sensory Perception Of Umami Taste Heat Generation Diet Induced Thermogenesis Cellular Response To Stimulus Receptor Guanylyl Cyclase Signaling Pathway Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Cellular Response To Electrical Stimulus Response To Light Intensity Detection Of Stimulus Involved In Sensory Perception Negative Regulation Of Smooth Muscle Contraction Adrenergic Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Response To Dietary Excess Negative Regulation Of Cation Channel Activity CGMP Biosynthetic Process
Tagcloud ?			0mg 5months accumulated amphetamine caloric calorimetry consumption dark dioxide expenditure factoring hour indicative indirect influences ko littermates locomotor male modulates opioid psychostimulant respective sensitization striatum utilize weights wt
Tagcloud (Difference) ?			0mg 5months accumulated amphetamine caloric calorimetry consumption dark dioxide expenditure factoring hour indicative indirect influences ko littermates locomotor male modulates opioid psychostimulant respective sensitization striatum utilize weights wt
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