GNAT1

Description		G protein subunit alpha transducin 1
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Membrane Apical Plasma Membrane Photoreceptor Connecting Cilium Photoreceptor Outer Segment Membrane Cell Projection Neuronal Cell Body Photoreceptor Disc Membrane
	Molecular Function	Acyl Binding Nucleotide Binding G Protein-coupled Receptor Binding GTPase Activity GTP Binding Guanyl Nucleotide Binding GDP Binding Protein Kinase Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Phototransduction, Visible Light Visual Behavior Cell Population Proliferation Response To Light Stimulus Detection Of Light Stimulus Response To Light Intensity Dopamine Secretion G Protein-coupled Opsin Signaling Pathway Regulation Of Opsin-mediated Signaling Pathway Eye Photoreceptor Cell Development Retinal Cone Cell Differentiation Detection Of Light Stimulus Involved In Visual Perception Sensory Perception Of Umami Taste Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Retina Development In Camera-type Eye Retinal Rod Cell Differentiation Cellular Response To Electrical Stimulus Neural Tissue Regeneration Background Adaptation
Pathways		Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade G alpha (i) signalling events
Drugs		Cacodylic acid Guanosine-5'-Diphosphate Tetrafluoroaluminate Ion
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS		Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Schizophrenia ( 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		1 novel interacting genes: ATXN7
Interacting Genes		3 interacting genes: F2R RGS16 RGS9
Entrez ID		2779
HPRD ID		08850
Ensembl ID		ENSG00000114349
Uniprot IDs		P11488
PDB IDs		3RBQ
Enriched GO Terms of Interacting Partners?		Visual Perception Sensory Perception Of Light Stimulus System Process Sensory Perception Dendritic Cell Homeostasis Negative Regulation Of Renin Secretion Into Blood Stream G Protein-coupled Receptor Signaling Pathway Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission Establishment Of Synaptic Specificity At Neuromuscular Junction Regulation Of Calcium Ion Transmembrane Transport Regulation Of G Protein-coupled Receptor Signaling Pathway Dark Adaptation Nervous System Process Platelet Dense Tubular Network Regulation Of Renin Secretion Into Blood Stream Light Adaption Negative Regulation Of Glomerular Filtration Thrombin-activated Receptor Activity Regulation Of Calcium Ion Transport Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Regulation Of Monoatomic Cation Transmembrane Transport GTPase Activator Activity Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Monoatomic Ion Transmembrane Transport GTPase Activity Connective Tissue Replacement Regulation Of Glomerular Filtration Regulation Of Metal Ion Transport Thrombin-activated Receptor Signaling Pathway Trans-synaptic Signaling, Modulating Synaptic Transmission Regulation Of Monoatomic Ion Transport Glutamate Secretion Response To Light Intensity Transcription Factor TFTC Complex Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Cell-cell Junction Maintenance G-protein Beta-subunit Binding G Protein-coupled Dopamine Receptor Signaling Pathway Positive Regulation Of Collagen Biosynthetic Process SAGA Complex Platelet Dense Granule Organization Positive Regulation Of Blood Coagulation Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Vasoconstriction Positive Regulation Of Coagulation Positive Regulation Of Smooth Muscle Contraction G-protein Alpha-subunit Binding Negative Regulation Of Microtubule Depolymerization Response To Amphetamine Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
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