HYAL2 and KRTAP3-2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HYAL2	KRTAP3-2
Gene Name		hyaluronoglucosaminidase 2	keratin associated protein 3-2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosome Endoplasmic Reticulum Cytosol Plasma Membrane Microvillus Cell Surface Cytoplasmic Membrane-bounded Vesicle Apical Plasma Membrane Endocytic Vesicle Anchored Component Of External Side Of Plasma Membrane Cytoplasmic Vesicle Membrane Raft Anchored Component Of Plasma Membrane Perinuclear Region Of Cytoplasm RNA Polymerase II Transcription Factor Complex	Keratin Filament
	Molecular Function	Virus Receptor Activity Hyalurononglucosaminidase Activity Protein Binding Hyaluronic Acid Binding Enzyme Binding Receptor Signaling Protein Tyrosine Kinase Inhibitor Activity Receptor Tyrosine Kinase Binding Hyaluronoglucuronidase Activity Transforming Growth Factor Beta Binding	Structural Molecule Activity Protein Binding
	Biological Process	Response To Reactive Oxygen Species Kidney Development Hematopoietic Progenitor Cell Differentiation Carbohydrate Metabolic Process Glycosaminoglycan Catabolic Process Pathogenesis Response To Virus Multicellular Organismal Aging Negative Regulation Of Fibroblast Migration Fusion Of Virus Membrane With Host Plasma Membrane Transformation Of Host Cell By Virus Glycosaminoglycan Metabolic Process Hyaluronan Metabolic Process Hyaluronan Catabolic Process Negative Regulation Of Cell Growth Positive Regulation Of Urine Volume Monocyte Activation Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of MAP Kinase Activity Small Molecule Metabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Antibiotic Viral Entry Into Host Cell Skeletal System Morphogenesis Positive Regulation Of Inflammatory Response Cartilage Development Defense Response To Virus Negative Regulation Of Protein Kinase B Signaling Multicellular Organismal Iron Ion Homeostasis Negative Regulation Of Protein Tyrosine Kinase Activity Renal Water Absorption Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To UV-B Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Interleukin-8 Secretion Positive Regulation Of Interleukin-6 Secretion Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Hyaluronan uptake and degradation Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Glycogen storage diseases MPS IIID - Sanfilippo syndrome D Hyaluronan metabolism Defective CHST6 causes MCDC1 MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS Metabolism of carbohydrates MPS VII - Sly syndrome MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: FHL3 KRTAP10-3 KRTAP3-2 MST1R	28 interactors: ARFGAP1 C5orf60 CNNM3 CREB5 DHRS1 HOXA1 HYAL2 KIF25-AS1 KRTAP10-1 KRTAP10-5 KRTAP12-2 KRTAP26-1 KRTAP4-12 KRTAP9-2 LCE1B LCE2A LCE3C LCE3E LCE4A MAPKBP1 NTM NUFIP2 OTX1 R3HDM2 TBC1D16 TRIM42 TRIP13 YIPF3
Entrez ID		8692	83897
HPRD ID		04649	13938
Ensembl ID		ENSG00000068001	ENSG00000212900
Uniprot IDs		Q12891	Q9BYR7
PDB IDs
Enriched GO Terms of Interacting Partners?		Macrophage Colony-stimulating Factor Signaling Pathway Cellular Response To Macrophage Colony-stimulating Factor Stimulus	Keratinization Keratinocyte Differentiation Epidermal Cell Differentiation Skin Development Epidermis Development Cell Differentiation Epithelial Cell Differentiation Developmental Process Organ Development Anatomical Structure Development Tissue Development System Development Multicellular Organismal Development Epithelium Development Optokinetic Behavior Abducens Nerve Formation Facial Nucleus Development Rhombomere 4 Development Fusion Of Virus Membrane With Host Plasma Membrane Transformation Of Host Cell By Virus Semicircular Canal Formation Inner Ear Morphogenesis Rhombomere 3 Development Rhombomere 5 Development Renal Water Absorption Ear Morphogenesis Metencephalon Development Renal Water Transport Diencephalon Morphogenesis Positive Regulation Of Interleukin-6 Secretion Positive Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		10a 184a1 184b5 3p21 cacna2d2 closest combinated demethylating deoxycytidine deregulated epigenetically flanking hyal1 hyal3 isoform nprl2 rassf1 rassf1a rassf1c sema3b seventeen silenced spearman tmem115 trichostatin trimethylated tusc2 unmethylated zmynd10
Tagcloud (Difference) ?		10a 184a1 184b5 3p21 cacna2d2 closest combinated demethylating deoxycytidine deregulated epigenetically flanking hyal1 hyal3 isoform nprl2 rassf1 rassf1a rassf1c sema3b seventeen silenced spearman tmem115 trichostatin trimethylated tusc2 unmethylated zmynd10
Tagcloud (Intersection) ?