KRT36 and KRT4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT36	KRT4
Description		keratin 36	keratin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Nucleus Cytosol Intermediate Filament Cell Surface Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization Regulation Of Keratinocyte Differentiation	Cytoskeleton Organization Epithelial Cell Differentiation Keratinization Intermediate Filament Organization Negative Regulation Of Epithelial Cell Proliferation
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			White sponge nevus
GWAS
Interacting Genes		60 interacting genes: ABI2 ABI3 AIMP2 AMOT APP BCAS2 C1orf216 CCBE1 CCHCR1 CDC23 DMRT3 EXOC8 GEM GPS2 HCK HGS HOXC8 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 MAP3K1 MYOZ1 MYOZ3 PKN1 PLEKHN1 PPP1R18 PSMB1 QARS1 RESF1 RIBC1 SMURF1 TMSB4X TRAF4 TSGA10IP TTC23 TTLL10 TXLNA ZNF414 ZNF785	22 interacting genes: C14orf119 CCDC57 CEP57 KIFC3 KRT14 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 PPP1R13B TRIM54 TUBGCP4
Entrez ID		8689	3851
HPRD ID		05174	00478
Ensembl ID		ENSG00000126337	ENSG00000170477
Uniprot IDs		O76013	P19013
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Cytosol Protein Binding Extracellular Exosome Epidermis Development Intermediate Filament Cytoskeleton Cornified Envelope FATZ Binding Tissue Development Telethonin Binding Actin-based Cell Projection Structural Constituent Of Cytoskeleton Aminoacyl-tRNA Synthetase Multienzyme Complex SCAR Complex Developmental Process Regulation Of Anatomical Structure Morphogenesis Peptidyl-tyrosine Phosphorylation	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Epithelial Cell Differentiation Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Structural Constituent Of Cytoskeleton Cell Differentiation Cellular Developmental Process Cytosol Hair Cycle Developmental Process Hair Follicle Morphogenesis Epidermis Development Hair Cycle Process Cell Periphery Microtubule Nucleation Centriolar Satellite Gamma-tubulin Binding Microtubule Intermediate Filament Polymerization Sulfite Oxidase Activity Protein Binding Intermediate Filament Polymerization Or Depolymerization Negative Regulation Of Entry Of Bacterium Into Host Cell Zonula Adherens Maintenance Terminal Web Molybdenum Ion Binding Keratinization Scaffold Protein Binding Microtubule Binding Molybdopterin Cofactor Binding
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