AOC3 and CLDN9

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		AOC3	CLDN9
Name		amine oxidase copper containing 3	claudin 9
Structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Microvillus Cell Surface Membrane	Plasma Membrane Bicellular Tight Junction Membrane Cell Junction Anchoring Junction
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Primary Methylamine Oxidase Activity Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Protein Heterodimerization Activity Quinone Binding	Virus Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Inflammatory Response Cell Adhesion Amine Metabolic Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Symbiont Entry Into Host Cell Bicellular Tight Junction Assembly Tight Junction Organization
Pathways		Phase I - Functionalization of compounds	Tight junction interactions
Drugs		Phenelzine Hydralazine 6-hydroxydopa quinone	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		13 interacting genes: ARL13B CLDN9 CPLX4 CREB3L1 DARS2 FNDC9 HSD17B13 LMNA MYBPC2 PRRG4 SGTA STX1A VAV1	17 interacting genes: ADIPOQ AOC3 ARLN BNIP3 CYB561 EMP1 ERMP1 EXTL1 GRM2 IGFBP5 LPAR3 MAL MALL PLPP6 RPRM STX8 VSTM1
Entrez ID		8639	9080
HPRD ID		04770	13071
Ensembl ID		ENSG00000131471	ENSG00000213937
Uniprot IDs		Q16853 Q9UEU7	O95484
PDB IDs		1PU4 1US1 2C10 2C11 2Y73 2Y74 3ALA 4BTW 4BTX 4BTY 8S1Z	6OV2 6OV3
GO Terms Enriched among Interactors		None	Endoplasmic Reticulum Bleb Assembly Structural Constituent Of Myelin Sheath Membrane Chemical Homeostasis Brown Fat Cell Differentiation Mitochondrion Autophagosome Adaptor Activity Negative Regulation Of Synaptic Transmission Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Homeostatic Process