CLDN9 and EXTL1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		CLDN9	EXTL1
Name		claudin 9	exostosin like glycosyltransferase 1
Structure			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Membrane Cell Junction Anchoring Junction	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Virus Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding Acetylglucosaminyltransferase Activity Glucuronosyltransferase Activity Transferase Activity Glycosyltransferase Activity Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Symbiont Entry Into Host Cell Bicellular Tight Junction Assembly Tight Junction Organization	Skeletal System Development Protein Glycosylation Heparan Sulfate Proteoglycan Biosynthetic Process
Pathways		Tight junction interactions	XBP1(S) activates chaperone genes
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		17 interacting genes: ADIPOQ AOC3 ARLN BNIP3 CYB561 EMP1 ERMP1 EXTL1 GRM2 IGFBP5 LPAR3 MAL MALL PLPP6 RPRM STX8 VSTM1	6 interacting genes: CLDN9 ERGIC3 FNDC9 SDR16C5 TMEM14B TMEM237
Entrez ID		9080	2134
HPRD ID		13071	03441
Ensembl ID		ENSG00000213937	ENSG00000158008
Uniprot IDs		O95484	Q92935
PDB IDs		6OV2 6OV3	Not available
GO Terms Enriched among Interactors		Endoplasmic Reticulum Bleb Assembly Structural Constituent Of Myelin Sheath Membrane Chemical Homeostasis Brown Fat Cell Differentiation Mitochondrion Autophagosome Adaptor Activity Negative Regulation Of Synaptic Transmission Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Homeostatic Process	None