TRIM29 and RNF13

Number of citations of the paper that reports this interaction (PubMedID 37857628)
58

Data Source:
BioGRID (pull down)

		TRIM29	RNF13
Description		tripartite motif containing 29	ring finger protein 13
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GO Annotations	Cellular Component	Cytoplasm Lysosome Adherens Junction	Nucleus Nuclear Inner Membrane Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Late Endosome Membrane
	Molecular Function	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Cadherin Binding Involved In Cell-cell Adhesion	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding JUN Kinase Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of JNK Cascade Organelle Localization Protein Autoubiquitination
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)	Fish- and plant-related diet ( 32066663) Myocardial infarction ( 26708285)
Interacting Genes		55 interacting genes: ACTN3 ANKS1A ATM CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF13 RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM	10 interacting genes: LGALS9 SNAPIN TRIM29 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N
Entrez ID		23650	11342
HPRD ID		10280	11503
Ensembl ID		ENSG00000137699	ENSG00000082996
Uniprot IDs		B7Z5V5 B7Z8U9 E9PRL4 Q14134	O43567
PDB IDs		2CSV	5ZBU 5ZC4
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Transcription Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Nucleus Cytoskeleton Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Viral Transcription Regulation Of Skeletal Muscle Fiber Development Protein Ubiquitination Positive Regulation Of DNA Recombination Cytosol Positive Regulation Of Metabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Development Somatic Cell DNA Recombination Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Autophagy Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA Recombination Signal Transduction By P53 Class Mediator Suppression Of Viral Release By Host Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Ligase Complex Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Intracellular Signal Transduction Double-strand Break Repair Via Nonhomologous End Joining Nucleoplasm Protein Modification Process Guanine/thymine Mispair Binding Positive Regulation Of Biosynthetic Process Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Positive Regulation Of Catabolic Process Protein Localization To Site Of Double-strand Break Positive Regulation Of Cell Development Regulation Of DNA Recombination Somatic Diversification Of Immunoglobulins Involved In Immune Response Regulation Of RNA Metabolic Process Negative Regulation Of Viral Process Macromolecule Catabolic Process Identical Protein Binding Protein Binding Signal Transduction In Response To DNA Damage Transcription Regulator Complex Positive Regulation Of Isotype Switching To IgA Isotypes	Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein Ubiquitination Protein Monoubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Protein K11-linked Ubiquitination ATP Binding Protein K63-linked Ubiquitination Protein Modification Process Macromolecule Catabolic Process Nucleotide Binding Transferase Activity Proteolysis Positive Regulation Of Protein Polyubiquitination Protein Metabolic Process Protein K6-linked Ubiquitination Regulation Of Protein Polyubiquitination Macromolecule Metabolic Process Catabolic Process Positive Regulation Of Activated T Cell Autonomous Cell Death Positive Regulation Of Late Endosome To Lysosome Transport TORC1 Signaling Negative Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Protein Autoubiquitination Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Involved In Immune Response Regulation Of DNA-templated Transcription Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Disaccharide Binding Ubiquitin Protein Ligase Activity TOR Signaling Negative Regulation Of Biosynthetic Process Negative Regulation Of TOR Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Natural Killer Cell Tolerance Induction Regulation Of TORC1 Signaling UBC13-MMS2 Complex Regulation Of RNA Metabolic Process Positive Regulation Of Protein Ubiquitination Ubiquitin Ligase Complex Positive Regulation Of DNA-binding Transcription Factor Activity
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