DGKE and MRPL44

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DGKE	MRPL44
Description		diacylglycerol kinase epsilon	mitochondrial ribosomal protein L44
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Glutamatergic Synapse	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Ribosome Plasma Membrane Nuclear Body Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding ATP-dependent Diacylglycerol Kinase Activity ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding	RNA Binding Double-stranded RNA Binding Nuclease Activity Endonuclease Activity Ribonuclease III Activity Protein Binding Hydrolase Activity
	Biological Process	Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerophospholipid Biosynthetic Process Glycerolipid Metabolic Process Lipid Phosphorylation Modulation Of Chemical Synaptic Transmission	RNA Processing Mitochondrial Translation Mitochondrial Translational Elongation
Pathways		Effects of PIP2 hydrolysis	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs		alpha-Tocopherol succinate
Diseases
GWAS		Crohn's disease ( 28067908) Early spontaneous preterm birth ( 31194736) Height ( 18391951) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Interacting Genes		2 interacting genes: HRAS MRPL44	21 interacting genes: ABI2 CEP70 DGKE DMRTB1 IMMT ITFG1 KRT31 NGEF PI4KA PLPP2 PRPF6 PRRC2B PTN QKI RBPMS SEMA5B SETDB1 SHC1 USP22 VIM ZNF235
Entrez ID		8526	65080
HPRD ID		03259	14763
Ensembl ID		ENSG00000153933	ENSG00000135900
Uniprot IDs		A1L4Q0 P52429	Q9H9J2
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Phospholipase C Activator Activity Ciliary Basal Body GTPase Complex Common Bile Duct Development Cell Surface Receptor Signaling Pathway Involved In Heart Development Smoothened Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Ribonuclease III Activity Mitochondrial Translational Elongation Oncogene-induced Cell Senescence
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