DGKE

Description		diacylglycerol kinase epsilon
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Glutamatergic Synapse
	Molecular Function	Nucleotide Binding ATP-dependent Diacylglycerol Kinase Activity ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerophospholipid Biosynthetic Process Glycerolipid Metabolic Process Lipid Phosphorylation Modulation Of Chemical Synaptic Transmission
Pathways		Effects of PIP2 hydrolysis
Drugs		alpha-Tocopherol succinate
Diseases
GWAS		Crohn's disease ( 28067908) Early spontaneous preterm birth ( 31194736) Height ( 18391951) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Novel Interacting Genes		1 novel interacting genes: MKS1
Interacting Genes		2 interacting genes: HRAS MRPL44
Entrez ID		8526
HPRD ID		03259
Ensembl ID		ENSG00000153933
Uniprot IDs		A1L4Q0 P52429
PDB IDs
Enriched GO Terms of Interacting Partners?		Phospholipase C Activator Activity Ciliary Basal Body GTPase Complex Common Bile Duct Development Cell Surface Receptor Signaling Pathway Involved In Heart Development Smoothened Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Ribonuclease III Activity Mitochondrial Translational Elongation Oncogene-induced Cell Senescence
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