NIPSNAP1 and TBC1D17

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		NIPSNAP1	TBC1D17
Gene Name		nipsnap homolog 1 (C. elegans)	TBC1 domain family, member 17
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Synaptic Membrane	Autophagic Vacuole Cytosol Cytoplasmic Vesicle
	Molecular Function	Neurotransmitter Binding	Rab GTPase Activator Activity Protein Binding
	Biological Process	Sensory Perception Of Pain	Autophagy Protein Transport Positive Regulation Of Rab GTPase Activity Retrograde Transport, Endosome To Golgi Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: DBI RGS2 TBC1D17	19 interactors: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1
Entrez ID		8508	79735
HPRD ID		10342	15471
Ensembl ID		ENSG00000184117	ENSG00000104946
Uniprot IDs		B4DQI7 Q9BPW8	Q9HA65
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Relaxation Of Vascular Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Microtubule Polymerization Relaxation Of Cardiac Muscle Negative Regulation Of Smooth Muscle Contraction Regulation Of Signaling Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Positive Regulation Of GTPase Activity Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Phosphatidylcholine Acyl-chain Remodeling Lateral Ventricle Development Regulation Of GTPase Activity Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Vasodilation Behavioral Fear Response Fear Response Brown Fat Cell Differentiation Positive Regulation Of Hydrolase Activity Ventricular System Development Long-term Synaptic Potentiation Regulation Of Smooth Muscle Contraction Phosphatidylcholine Metabolic Process Termination Of G-protein Coupled Receptor Signaling Pathway Retrograde Transport, Endosome To Golgi Termination Of Signal Transduction Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Cardiac Muscle Contraction Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Multicellular Organismal Response To Stress Triglyceride Metabolic Process Hair Follicle Development Positive Regulation Of Catalytic Activity Hair Cycle Process Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Neutral Lipid Metabolic Process	Macroautophagy Autophagic Vacuole Assembly Cellular Response To Starvation Rab Protein Signal Transduction Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Nucleophagy Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Mitochondrion Degradation Organelle Disassembly Plasma Membrane To Endosome Transport Ras Protein Signal Transduction Response To External Stimulus Cellular Response To Nitrogen Starvation Cellular Response To Stress Membrane Fusion Cytoplasmic Transport Regulation Of Endocytosis Membrane Organization Organelle Assembly Response To Stimulus Endosomal Transport Intracellular Protein Transport Response To Stress Histone Glutamine Methylation Extracellular Amino Acid Transport Small GTPase Mediated Signal Transduction Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Peptidyl-glutamine Methylation Golgi Organization Response To Other Organism Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Response To Biotic Stimulus Regulation Of Vesicle-mediated Transport Interleukin-8 Production SnoRNA Metabolic Process Negative Regulation Of Receptor Recycling Cellular Protein Localization Mitochondrion Organization Protein Transport Negative Regulation Of Intracellular Signal Transduction Vesicle-mediated Transport Endomembrane System Organization 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
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