MEDAG and SYNJ2BP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MEDAG	SYNJ2BP
Description		mesenteric estrogen dependent adipogenesis	synaptojanin 2 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Fat Cell Differentiation	Negative Regulation Of Endothelial Cell Proliferation Protein Targeting Rho Protein Signal Transduction Regulation Of Notch Signaling Pathway Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Endocytosis Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS		Influenza A (H1N1) infection ( 26379185) Mild influenza (H1N1) infection ( 26379185)	Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Motor coordination ( 34177493) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		4 interacting genes: ATPAF2 CATIP SYNJ2BP TOLLIP	34 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1 VANGL2
Entrez ID		84935	55333
HPRD ID		07872	15455
Ensembl ID		ENSG00000102802	ENSG00000213463
Uniprot IDs		Q5VYS4	P57105
PDB IDs			2ENO 2JIK 2JIN 7P73 7P74 7PC9 7R2M 7R2T 8AEL
Enriched GO Terms of Interacting Partners?			Membrane Receptor Complex Low-density Lipoprotein Particle Receptor Activity Apolipoprotein Binding Activin Receptor Activity, Type II Activin Receptor Activity Endocytosis Import Into Cell Astrocyte Activation Involved In Immune Response Cargo Receptor Activity Long-chain Fatty-acyl-CoA Metabolic Process Positive Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Activin Receptor Signaling Pathway Activin Receptor Complex Positive Regulation Of Protein Catabolic Process In The Vacuole Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Protein Binding Activin Binding Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Developmental Process Cellular Response To Growth Factor Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Activity Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Apical Protein Localization Response To Growth Factor Clathrin-coated Pit Vesicle-mediated Transport Plasma Membrane Protein Complex Receptor-mediated Endocytosis Retinoid Metabolic Process Regulation Of Developmental Process Gastrulation With Mouth Forming Second Heparan Sulfate Proteoglycan Binding Astrocyte Activation Transport Across Blood-brain Barrier Diterpenoid Metabolic Process Fatty Acid Derivative Metabolic Process Endoplasmic Reticulum Transcytosis Long-chain Fatty-acyl-CoA Biosynthetic Process Regulation Of Amyloid-beta Clearance Regulation Of Cell Differentiation Acyl-CoA Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress
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