SLC35B4 and RHBDL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC35B4	RHBDL2
Description		solute carrier family 35 member B4	rhomboid like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	UDP-N-acetylglucosamine Transmembrane Transporter Activity UDP-xylose Transmembrane Transporter Activity Protein Binding	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Regulation Of Gluconeogenesis UDP-xylose Transmembrane Transport Transmembrane Transport UDP-N-acetylglucosamine Transmembrane Transport	Proteolysis
Pathways		Transport of nucleotide sugars
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252 32888494) Plateletcrit ( 32888494) Systolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)	Beard thickness ( 26926045) Menopause (age at onset) ( 22267201 26414677) Severe autoimmune type 2 diabetes ( 34737425) Sweet beverage consumption ( 31046077) Triglyceride levels ( 32203549)
Interacting Genes		34 interacting genes: AQP6 CD79A CFTR CISD2 CLDN5 CPLX4 CREB3L1 EBAG9 ERGIC3 ERP29 FAM209A FAM210B FFAR2 GPR152 GPX8 HSD17B13 KASH5 LHFPL5 LMNA MMGT1 MUC1 PDZK1IP1 PVR RHBDL2 SCARA5 SLC10A6 SLC18A1 STOM TBXA2R TMEM130 TMEM237 TMEM52B TYROBP VSIR	4 interacting genes: EFNB2 EFNB3 SLC35B4 TMBIM6
Entrez ID		84912	54933
HPRD ID		11578	07151
Ensembl ID		ENSG00000205060	ENSG00000158315
Uniprot IDs		Q969S0	B7Z1Y9 Q9NX52
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane	T Cell Costimulation Ephrin Receptor Signaling Pathway Ephrin Receptor Binding Virus Receptor Activity Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress UDP-xylose Transmembrane Transport UDP-xylose Transmembrane Transporter Activity Positive Regulation Of Aorta Morphogenesis Presynaptic Membrane Symbiont Entry Into Host Cell Negative Regulation Of Neuron Projection Development Endoribonuclease Inhibitor Activity Biological Process Involved In Interaction With Host UDP-N-acetylglucosamine Transmembrane Transporter Activity UDP-N-acetylglucosamine Transmembrane Transport Negative Regulation Of Cell Projection Organization Regulation Of Aorta Morphogenesis Negative Regulation Of Calcium Ion Transport Into Cytosol Neuron Projection Guidance Axon Guidance Positive Regulation Of Artery Morphogenesis Trans-synaptic Signaling By Trans-synaptic Complex Axon Choice Point Recognition Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of T Cell Activation Venous Blood Vessel Morphogenesis Nephric Duct Morphogenesis Regulation Of Artery Morphogenesis Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cardiac Muscle Cell Differentiation IRE1-mediated Unfolded Protein Response Pyrimidine Nucleotide-sugar Transmembrane Transport Nucleotide-sugar Transmembrane Transport Lymph Vessel Development Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Presynapse Assembly Trans-synaptic Signaling, Modulating Synaptic Transmission Negative Regulation Of Cellular Response To Hypoxia Negative Regulation Of Immunoglobulin Production Positive Regulation Of Cardiocyte Differentiation Transmembrane-ephrin Receptor Activity Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Leukocyte Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Cell Activation Transmembrane Receptor Protein Tyrosine Kinase Activator Activity
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