TRIM52 and RNF114

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		TRIM52	RNF114
Gene Name		tripartite motif containing 52	ring finger protein 114
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Intracellular Nucleus Cytoplasm
	Molecular Function	Zinc Ion Binding	Zinc Ion Binding Ligase Activity
	Biological Process	Positive Regulation Of NF-kappaB Transcription Factor Activity	Multicellular Organismal Development Spermatogenesis Protein Ubiquitination Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Psoriasis ( 20953189)
Protein-Protein Interactions		5 interactors: APP NEDD4 RNF114 RNF126 TRIM41	26 interactors: AK5 BMI1 EVI2A MAPK3 RNF38 RPSA TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W UEVLD XAF1
Entrez ID		84851	55905
HPRD ID		10283	10329
Ensembl ID			ENSG00000124226
Uniprot IDs		L0CQ38 Q96A61	Q9Y508
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein Monoubiquitination Neuromuscular Junction Development Cellular Protein Modification Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Synapse Structure Or Activity Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Protein Metabolic Process Synaptic Growth At Neuromuscular Junction Protein Polyubiquitination Synapse Organization Collateral Sprouting In Absence Of Injury Intracellular Receptor Signaling Pathway Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Progesterone Receptor Signaling Pathway Axon Choice Point Recognition Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Glucocorticoid Receptor Signaling Pathway Neuron Remodeling Response To Light Stimulus Vesicle-mediated Transport Intracellular Transport Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Protein Localization To Lysosome Response To Misfolded Protein Response To Radiation Cellular Copper Ion Homeostasis Receptor Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Targeting To Vacuole Copper Ion Homeostasis Suckling Behavior Regulation Of Neuron Differentiation Proteolysis Involved In Cellular Protein Catabolic Process	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Protein Modification Process Cellular Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Catabolic Process Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Innate Immune Response Protein K63-linked Ubiquitination Regulation Of Innate Immune Response Positive Regulation Of Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Ligase Activity Cellular Response To Stress Proteolysis Regulation Of Protein Ubiquitination Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Apoptotic Process Cellular Response To Oxygen Levels Programmed Cell Death Histone Ubiquitination Catabolic Process Immune Response-regulating Signaling Pathway Cell Death Death Protein Monoubiquitination Innate Immune Response
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