TRIM52

Description		tripartite motif containing 52
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Signal Transduction Protein Ubiquitination Positive Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Positive Regulation Of DNA-templated Transcription Defense Response To Virus Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: APP NEDD4 RNF114 RNF126 RSPH1 TRIM41
Entrez ID		84851
HPRD ID		10283
Ensembl ID		ENSG00000183718
Uniprot IDs		A0A8I5KQM7 A0A8I5KRY2 A0A8I5KW90 A0A8I5KXQ2 A0A8I5KYD8 Q96A61
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Monoubiquitination Ubiquitin Protein Ligase Activity Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Polyubiquitination Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein K63-linked Ubiquitination Formation Of Structure Involved In A Symbiotic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Innate Immune Response Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Cytosol Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Protein Modification Process Modification-dependent Protein Catabolic Process Channel Inhibitor Activity Phosphothreonine Residue Binding Ubiquitin-dependent Protein Catabolic Process Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System Radial Spoke Head 1 Radial Spoke Head 3 Proteolysis Involved In Protein Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Defense Response To Symbiont Axon Midline Choice Point Recognition Defense Response To Other Organism Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling
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