TXNDC17 and PIGS

		TXNDC17	PIGS
Description		thioredoxin domain containing 17	phosphatidylinositol glycan anchor biosynthesis class S
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GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function	Peroxidase Activity Protein Binding Protein-disulfide Reductase [NAD(P)H] Activity	Protein Binding
	Biological Process	Tumor Necrosis Factor-mediated Signaling Pathway Cellular Oxidant Detoxification	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis
Pathways			Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		9 interacting genes: AVP DYNLL1 EXOSC8 INCA1 INS OXT RUFY1 TINF2 TXNRD1	14 interacting genes: CPEB2 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP19-2 KRTAP2-3 KRTAP2-4 KRTAP6-3 KRTAP9-2 NBPF19 NOTCH2NLA TRIP6
Entrez ID		84817	94005
HPRD ID		11656	15135
Ensembl ID		ENSG00000129235	ENSG00000087111
Uniprot IDs		A0A140VJY7 Q9BRA2	Q8NBL9 Q96IR5 Q96S52
PDB IDs		1WOU	7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		Neurohypophyseal Hormone Activity Maternal Aggressive Behavior Regulation Of Female Receptivity Female Mating Behavior Aggressive Behavior Grooming Behavior Positive Regulation Of Secretion Hormone Activity Positive Regulation Of Secretion By Cell Maternal Behavior Parental Behavior Secretory Granule Mating Behavior Neuronal Dense Core Vesicle Neuropeptide Hormone Activity Positive Regulation Of Blood Pressure Reproductive Behavior Identical Protein Binding Response To Electrical Stimulus Regulation Of Secretion By Cell Regulation Of Secretion Social Behavior V1B Vasopressin Receptor Binding Positive Regulation Of Hindgut Contraction Oxytocin Receptor Binding NADPH Peroxidase Activity Positive Regulation Of Transport Regulation Of Amine Transport V1A Vasopressin Receptor Binding Regulation Of Transport Negative Regulation Of Glycogen Catabolic Process Regulation Of Hindgut Contraction Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Perinucleolar Chromocenter Positive Regulation Of Lipid Biosynthetic Process Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Penile Erection Positive Regulation Of Norepinephrine Secretion Positive Regulation Of Female Receptivity Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Positive Regulation Of Cell Growth Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Vessel Diameter Maintenance	Intermediate Filament Keratin Filament
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