CFP

Gene Name		complement factor properdin
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function
	Biological Process	Protein O-linked Glycosylation Immune Response Complement Activation Complement Activation, Alternative Pathway Regulation Of Complement Activation Protein O-linked Fucosylation Defense Response To Bacterium Post-translational Protein Modification Cellular Protein Metabolic Process Innate Immune Response
Pathways		Alternative complement activation Regulation of Complement cascade Post-translational protein modification Complement cascade Activation of C3 and C5 O-glycosylation of TSR domain-containing proteins Initial triggering of complement Innate Immune System O-linked glycosylation
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: C3 CFB MTOR
Entrez ID		5199
HPRD ID		02308
Ensembl ID		ENSG00000126759
Uniprot IDs		P27918
PDB IDs		1W0R 1W0S
Enriched GO Terms of Interacting Partners?		Complement Activation, Alternative Pathway Regulation Of Complement Activation Regulation Of Humoral Immune Response Regulation Of Acute Inflammatory Response Innate Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Lipid Biosynthetic Process Complement Activation Regulation Of Carbohydrate Utilization Protein Activation Cascade Immune Response Regulation Of Immune System Process Defense Response Positive Regulation Of Type IIa Hypersensitivity Humoral Immune Response Regulation Of Inflammatory Response Regulation Of Lipid Metabolic Process Positive Regulation Of Activation Of Membrane Attack Complex Immune System Process Positive Regulation Of Hypersensitivity Regulation Of Protein Metabolic Process Regulation Of Protein Processing Negative Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Apoptotic Cell Clearance Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Apoptotic Cell Clearance Negative Regulation Of Macroautophagy Positive Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of Lamellipodium Assembly Negative Regulation Of Cell Size Positive Regulation Of Humoral Immune Response Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Lamellipodium Organization Positive Regulation Of Immune Response Regulation Of Response To Food Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Processing Regulation Of Triglyceride Biosynthetic Process Regulation Of Rac GTPase Activity TOR Signaling Positive Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Lamellipodium Assembly Response To Stress Positive Regulation Of Acute Inflammatory Response Regulation Of Cellular Response To Heat Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation
Tagcloud ?		antigens cd4 confirming counts derivative donors fell filtrate h37rv hiv inducers kd mantoux mm3 mtbs mycobacterial portuguese ppd pulmonary retained secreted sonicate st stronger strongest supernatants switch tb th1