LPCAT2

Description		lysophosphatidylcholine acyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Lipid Droplet Plasma Membrane Membrane Organelle Subcompartment
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Calcium Ion Binding Protein Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity Metal Ion Binding 2-acylglycerol-3-phosphate O-acyltransferase Activity Plasmalogen Synthase Activity 1-acylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acetyltransferase Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Platelet Activating Factor Biosynthetic Process Phospholipid Biosynthetic Process Phosphatidylcholine Acyl-chain Remodeling Membrane Organization
Pathways		Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Thyroid hormone levels ( 23408906)
Interacting Genes		8 interacting genes: CREB3 EBP ERGIC3 HSD17B13 KCNJ6 RETREG3 RHBDD1 SLC71A2
Entrez ID		54947
HPRD ID		07913
Ensembl ID		ENSG00000087253
Uniprot IDs		Q7L5N7
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Response To Unfolded Protein Positive Regulation Of Deacetylase Activity C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Retrograde Transporter Complex, Golgi To ER Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Steroid Delta-isomerase Activity Steroid Dehydrogenase Activity G-protein Activated Inward Rectifier Potassium Channel Activity Transporter Complex Endoplasmic Reticulum-autophagosome Adaptor Activity Release From Viral Latency Regulation Of Male Germ Cell Proliferation CCR1 Chemokine Receptor Binding Regulation Of Germ Cell Proliferation
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