GOLPH3 and GLT8D1

Number of citations: 68 (PubMedID 34473204)
Data Source: BioGRID (pull down)

		GOLPH3	GLT8D1
Name		golgi phosphoprotein 3	glycosyltransferase 8 domain containing 1
Structure			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Mitochondrial Intermembrane Space Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Membrane Golgi Cisterna Golgi Cisterna Membrane	Golgi Apparatus Membrane
	Molecular Function	Protein Binding Lipid Binding Enzyme Binding Phosphatidylinositol-4-phosphate Binding Cargo Adaptor Activity	UDP-glycosyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Glycoprotein Biosynthetic Process Protein Secretion Gene Expression Regulation Of Mitochondrion Organization Protein Transport Cell Migration Lamellipodium Assembly Positive Regulation Of TOR Signaling Golgi To Plasma Membrane Protein Transport Negative Regulation Of Apoptotic Process Protein Retention In Golgi Apparatus Golgi Vesicle Budding Positive Regulation Of Protein Secretion Leukocyte Tethering Or Rolling Cell Adhesion Molecule Production Cellular Response To Rapamycin Golgi Ribbon Formation Asymmetric Golgi Ribbon Formation Protein Targeting To Golgi Apparatus	None
GWAS		Metabolite levels ( 23823483 )	A body shape index ( 34021172 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Bipolar disorder ( 21926972 31043756 ) Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Osteoarthritis ( 22763110 ) Osteoarthritis of the hip or knee ( 30664745 ) Pulse pressure ( 27841878 ) Schizophrenia ( 29483656 28991256 25056061 23974872 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 ) Systolic blood pressure ( 27841878 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Interacting Genes		23 interacting genes: ARL6IP1 B4GALT4 C1GALT1 CANT1 DIPK2A EBAG9 EXT1 FAM20B FAM3C GALNT2 GALNT6 GALNT7 GCNT1 GLG1 GLT8D1 GOLIM4 GOLM2 MAN1B1 MGAT2 PGAP4 POMGNT1 TPST1 TPST2	2 interacting genes: GOLPH3 GOLPH3L
Entrez ID		64083	55830
HPRD ID		11007	12423
Ensembl ID		ENSG00000113384	ENSG00000016864
Uniprot IDs		Q9H4A6	Q68CQ7 Q7Z4D0
PDB IDs		3KN1	Not available
GO Terms Enriched among Interactors		Golgi Apparatus Golgi Membrane Glycoprotein Metabolic Process Glycosyltransferase Activity Glycoprotein Biosynthetic Process Protein Glycosylation Macromolecule Glycosylation Carbohydrate Derivative Metabolic Process Glycosylation Carbohydrate Derivative Biosynthetic Process Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine Transferase Activity Macromolecule Biosynthetic Process Protein Modification Process Protein Metabolic Process Membrane Polypeptide N-acetylgalactosaminyltransferase Activity Proteoglycan Biosynthetic Process Protein-tyrosine Sulfotransferase Activity Carbohydrate Binding Proteoglycan Metabolic Process Macromolecule Metabolic Process Manganese Ion Binding Golgi Cisterna Membrane Carbohydrate Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Leukocyte Tethering Or Rolling Golgi Lumen Leukocyte Adhesion To Vascular Endothelial Cell Viral Protein Processing Basement Membrane Organization Bone Morphogenesis Lymphocyte Adhesion To Endothelial Cell Of High Endothelial Venule Perichondral Bone Morphogenesis Sweat Gland Development Smoothened Signaling Pathway Involved In Lung Development Golgi Stack Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Peptidyl-tyrosine Sulfation Trans-Golgi Network Protein Homodimerization Activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase Activity Mesenchymal Cell Differentiation Involved In Bone Development Stomach Development Heparan Sulfate N-acetylglucosaminyltransferase Activity Leukocyte Cell-cell Adhesion	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Trans-Golgi Network Protein Localization To Plasma Membrane Protein Targeting Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Positive Regulation Of Protein Transport Regulation Of Protein Secretion Asymmetric Golgi Ribbon Formation Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Cell Adhesion Molecule Production Cellular Response To Rapamycin Lipid Binding Establishment Of Protein Localization To Organelle Protein Retention In Golgi Apparatus Regulation Of Protein Transport Positive Regulation Of Protein Localization Response To Rapamycin Localization Within Membrane Regulation Of Establishment Of Protein Localization Regulation Of Secretion By Cell Golgi Ribbon Formation Cellular Response To Ether Regulation Of Secretion Golgi Membrane Membrane Organization Positive Regulation Of Transport Leukocyte Tethering Or Rolling Response To Ether Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Protein Localization