GOLPH3 and GCNT1

Number of citations of the paper that reports this interaction (PubMedID 34473204)
68

Data Source:
BioGRID (pull down)

		GOLPH3	GCNT1
Description		golgi phosphoprotein 3	glucosaminyl (N-acetyl) transferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Mitochondrial Intermembrane Space Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Membrane Golgi Cisterna Golgi Cisterna Membrane	Golgi Membrane Extracellular Space Golgi Apparatus Trans-Golgi Network Membrane Golgi Cisterna
	Molecular Function	Protein Binding Lipid Binding Enzyme Binding Phosphatidylinositol-4-phosphate Binding Cargo Adaptor Activity	Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity Protein Binding UDP-glycosyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Glycoprotein Biosynthetic Process Protein Secretion Gene Expression Regulation Of Mitochondrion Organization Protein Transport Cell Migration Lamellipodium Assembly Positive Regulation Of TOR Signaling Golgi To Plasma Membrane Protein Transport Negative Regulation Of Apoptotic Process Protein Retention In Golgi Apparatus Golgi Vesicle Budding Positive Regulation Of Protein Secretion Leukocyte Tethering Or Rolling Cell Adhesion Molecule Production Cellular Response To Rapamycin Golgi Ribbon Formation Asymmetric Golgi Ribbon Formation Protein Targeting To Golgi Apparatus	Protein Glycosylation Glycoprotein Biosynthetic Process Protein O-linked Glycosylation Via N-acetyl-galactosamine Response To Insulin Tissue Morphogenesis Leukocyte Tethering Or Rolling Cell Adhesion Molecule Production Kidney Morphogenesis Positive Regulation Of Leukocyte Tethering Or Rolling
Pathways			O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289) D-dimer levels in HIV infection ( 33095540) Dialysis-related mortality ( 21546767) Monocyte count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		23 interacting genes: ARL6IP1 B4GALT4 C1GALT1 CANT1 DIPK2A EBAG9 EXT1 FAM20B FAM3C GALNT2 GALNT6 GALNT7 GCNT1 GLG1 GLT8D1 GOLIM4 GOLM2 MAN1B1 MGAT2 PGAP4 POMGNT1 TPST1 TPST2	3 interacting genes: GOLPH3 GOLPH3L PRKCB
Entrez ID		64083	2650
HPRD ID		11007	02669
Ensembl ID		ENSG00000113384	ENSG00000187210
Uniprot IDs		Q9H4A6	Q02742
PDB IDs		3KN1
Enriched GO Terms of Interacting Partners?		Golgi Apparatus Golgi Membrane Glycoprotein Metabolic Process Glycosyltransferase Activity Glycoprotein Biosynthetic Process Protein Glycosylation Macromolecule Glycosylation Carbohydrate Derivative Metabolic Process Glycosylation Carbohydrate Derivative Biosynthetic Process Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine Transferase Activity Macromolecule Biosynthetic Process Protein Modification Process Protein Metabolic Process Membrane Polypeptide N-acetylgalactosaminyltransferase Activity Proteoglycan Biosynthetic Process Protein-tyrosine Sulfotransferase Activity Carbohydrate Binding Proteoglycan Metabolic Process Macromolecule Metabolic Process Manganese Ion Binding Golgi Cisterna Membrane Carbohydrate Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Leukocyte Tethering Or Rolling Golgi Lumen Leukocyte Adhesion To Vascular Endothelial Cell Viral Protein Processing Basement Membrane Organization Bone Morphogenesis Lymphocyte Adhesion To Endothelial Cell Of High Endothelial Venule Perichondral Bone Morphogenesis Sweat Gland Development Smoothened Signaling Pathway Involved In Lung Development Golgi Stack Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Peptidyl-tyrosine Sulfation Trans-Golgi Network Protein Homodimerization Activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase Activity Mesenchymal Cell Differentiation Involved In Bone Development Stomach Development Heparan Sulfate N-acetylglucosaminyltransferase Activity Leukocyte Cell-cell Adhesion	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Positive Regulation Of Protein Secretion Positive Regulation Of Protein Transport Regulation Of Protein Secretion Positive Regulation Of Secretion Positive Regulation Of Secretion By Cell Positive Regulation Of Establishment Of Protein Localization Golgi To Plasma Membrane Protein Transport Phosphatidylinositol-4-phosphate Binding Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Positive Regulation Of Protein Localization Regulation Of Protein Transport Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Regulation Of Establishment Of Protein Localization Regulation Of Secretion By Cell Regulation Of Secretion Membrane Organization Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Transport Histone H3T6 Kinase Activity Asymmetric Golgi Ribbon Formation Regulation Of Protein Localization Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Localization To Plasma Membrane Protein Targeting Establishment Of Protein Localization To Membrane Protein Transport Protein Kinase C Signaling Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery MCRD-mediated MRNA Stability Complex RISC Complex Binding Nuclear-transcribed MRNA Catabolic Process, No-go Decay CRD-mediated MRNA Stability Complex Response To Rapamycin Establishment Of Protein Localization Golgi Vesicle Transport Golgi Apparatus Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway
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