GON7 and LAGE3

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		GON7	LAGE3
Description		GON7 subunit of KEOPS complex	L antigen family member 3
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GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Nucleoplasm Nucleolus Cytosol	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	TRNA Threonylcarbamoyladenosine Modification	TRNA Processing TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		tRNA modification in the nucleus and cytosol	tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: LAGE3	22 interacting genes: AKAP8L CYSRT1 GOLGA6L9 GON7 HSF2BP HYKK KRT40 KRTAP10-8 KRTAP6-3 MID2 MIPOL1 MKRN3 OSGEP PDE9A PLEKHJ1 PNMA1 POP7 PSMB9 TRIM23 TRIM27 TRIM55 VPS37C
Entrez ID		84520	8270
HPRD ID		16608	02087
Ensembl ID		ENSG00000170270	ENSG00000196976
Uniprot IDs		Q9BXV9	Q14657
PDB IDs		6GWJ	6GWJ
Enriched GO Terms of Interacting Partners?		EKC/KEOPS Complex TRNA Threonylcarbamoyladenosine Metabolic Process TRNA Processing	EKC/KEOPS Complex TRNA Threonylcarbamoyladenosine Modification Ubiquitin Protein Ligase Activity Identical Protein Binding Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Regulation Of Viral Transcription TRNA Threonylcarbamoyladenosine Metabolic Process TRNA Processing Protein Ubiquitination Intermediate Filament Amino Acid Kinase Activity Hydroxylysine Kinase Activity Positive Regulation Of Autophagy Protein Modification By Small Protein Conjugation
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