LAGE3 and OSGEP

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		LAGE3	OSGEP
Description		L antigen family member 3	O-sialoglycoprotein endopeptidase
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GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Nuclear Body	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Metal Ion Binding TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity
	Biological Process	TRNA Processing TRNA Threonylcarbamoyladenosine Metabolic Process	TRNA Threonylcarbamoyladenosine Modification TRNA Modification TRNA Processing
Pathways		tRNA modification in the nucleus and cytosol	tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS			Food addiction ( 27106561)
Interacting Genes		22 interacting genes: AKAP8L CYSRT1 GOLGA6L9 GON7 HSF2BP HYKK KRT40 KRTAP10-8 KRTAP6-3 MID2 MIPOL1 MKRN3 OSGEP PDE9A PLEKHJ1 PNMA1 POP7 PSMB9 TRIM23 TRIM27 TRIM55 VPS37C	25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 LGALS4 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 WDR82 WIZ ZNF579 ZNF775
Entrez ID		8270	55644
HPRD ID		02087	10133
Ensembl ID		ENSG00000196976	ENSG00000092094
Uniprot IDs		Q14657	Q9NPF4
PDB IDs		6GWJ	6GWJ
Enriched GO Terms of Interacting Partners?		EKC/KEOPS Complex TRNA Threonylcarbamoyladenosine Modification Ubiquitin Protein Ligase Activity Identical Protein Binding Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Regulation Of Viral Transcription TRNA Threonylcarbamoyladenosine Metabolic Process TRNA Processing Protein Ubiquitination Intermediate Filament Amino Acid Kinase Activity Hydroxylysine Kinase Activity Positive Regulation Of Autophagy Protein Modification By Small Protein Conjugation
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