ABLIM2 and ABRA

Number of citations of the paper that reports this interaction (PubMedID 17194709)
0

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ABLIM2	ABRA
Description		actin binding LIM protein family member 2	actin binding Rho activating protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton	Cytoplasm Cytoskeleton Plasma Membrane Actin Cytoskeleton Myofibril Sarcomere
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding	Actin Binding Protein Binding
	Biological Process	Cytoskeleton Organization Lamellipodium Assembly	Transcription By RNA Polymerase II Protein Import Into Nucleus Protein Transport Actin Cytoskeleton Organization Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		DCC mediated attractive signaling
Drugs
Diseases
GWAS		Cognitive function ( 28808816) Diffusing capacity of carbon monoxide ( 30694715) Early onset periodontitis x smoking status interaction ( 31537151) Irritable bowel syndrome ( 29626450) Post bronchodilator FEV1 in COPD ( 26634245) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Triacylglyceride levels ( 31551469)	Dental caries ( 23259602) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Intraocular pressure ( 30054594 31959993) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: ABRA AHNAK2 ATP6V0A1 MLIP SREBF2 TTN	6 interacting genes: ABLIM2 ACTA1 ACTB ACTC1 PPP1R18 TRAPPC2
Entrez ID		84448	137735
HPRD ID		10623	11608
Ensembl ID		ENSG00000163995	ENSG00000174429
Uniprot IDs		A0A140VK02 F5GYR0 Q6H8Q1	Q8N0Z2
PDB IDs		1V6G 1WIG 2L3X
Enriched GO Terms of Interacting Partners?		Endosomal Lumen Acidification Proton-transporting V-type ATPase, V0 Domain Cytoplasm Regulation Of Macroautophagy Regulation Of Metabolic Process Regulation Of Autophagy Synaptic Vesicle Lumen Acidification Proton-transporting V-type ATPase Complex Vacuolar Proton-transporting V-type ATPase, V0 Domain Vacuolar Proton-transporting V-type ATPase Complex Positive Regulation Of Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process Response To Sterol Depletion Regulation Of Amyloid-beta Clearance Negative Regulation Of Amyloid-beta Clearance Positive Regulation Of Cholesterol Storage SREBP Signaling Pathway Negative Regulation Of Cholesterol Efflux Regulation Of Gene Expression Positive Regulation Of Lipid Storage Cellular Response To Laminar Fluid Shear Stress Cellular Response To Sterol Depletion SREBP-SCAP-Insig Complex C-8 Sterol Isomerase Activity Negative Regulation Of Cholesterol Transport Positive Regulation Of Macromolecule Biosynthetic Process Response To Laminar Fluid Shear Stress Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Establishment Of Protein Localization Titin-telethonin Complex Protein Kinase A Signaling Muscle Alpha-actinin Binding Mitotic Chromosome Condensation Detection Of Muscle Stretch Protein Kinase Regulator Activity Structural Molecule Activity Conferring Elasticity Actin-myosin Filament Sliding Striated Muscle Thin Filament Myosin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Actin Cytoskeleton Organization Actin Cytoskeleton Cardiac Myofibril Assembly Sarcomerogenesis Muscle Filament Sliding Actinin Binding Telethonin Binding Skeletal Muscle Thin Filament Assembly Sarcolemma Regulation Of Cardiac Muscle Hypertrophy In Response To Stress	Actin Filament Actin Cytoskeleton Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Blood Microparticle Lamellipodium Myosin Binding Sarcomere Filopodium Cell Body Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Structural Constituent Of Cytoskeleton Cytoskeleton Regulation Of Norepinephrine Uptake Transporter Regulator Activity Regulation Of Transepithelial Transport Protein Localization To Adherens Junction Dense Body Cytoplasmic Actin-based Contraction Involved In Cell Motility Muscle Contraction Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Striated Muscle Thin Filament Muscle System Process Actin Filament Organization BBAF Complex Tat Protein Binding Nitric-oxide Synthase Regulator Activity Postsynaptic Actin Cytoskeleton Cytoskeleton Organization Cytoplasm Brahma Complex Nitric-oxide Synthase Binding Apical Protein Localization RSC-type Complex Adherens Junction Assembly NpBAF Complex GBAF Complex Cellular Component Assembly Cardiac Myofibril Assembly TRAPPII Protein Complex TRAPP Complex TRAPPIII Protein Complex Organelle Organization NBAF Complex Postsynaptic Actin Cytoskeleton Organization Actin-myosin Filament Sliding Actin Cytoskeleton Organization Protein Localization To Cell-cell Junction
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